Incidence and risk factors for hospital-acquired Clostridium difficile infection among inpatients in an orthopaedic tertiary care hospital
Incidence and risk factors for hospital-acquired Clostridium difficile infection among inpatients in an orthopaedic tertiary care hospital
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DOI：
10.1016/j.jhin.2012.11.009
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发表时间：
2013-02-01
影响因子：
6.9
通讯作者：
Mehta, S. A.
中科院分区：
文献类型：
--
作者：
Campbell, K. A.;Phillips, M. S.;Mehta, S. A.
这项回顾性研究的目的是确定骨科患者医院获得性艰难梭菌感染 (HA-CDI) 的危险因素。 32 例 HA-CDI 病例每例均与 2 例对照相匹配。发病率为每 1000 患者日 0.33 例。单变量分析显示，入院后 >24 小时进行手术、使用抗生素治疗和质子泵抑制剂与 HA-CDI 相关。多变量分析显示，入院后 24 小时以上的手术与 HA-CDI 相关。术前住院的患者发生 HA-CDI 的风险较高，这表明有机会通过在门诊环境中及时进行术前医疗优化来减少艰难梭菌的环境暴露。 (C) 2012 年医疗保健感染协会。由爱思唯尔有限公司出版。保留所有权利。
The aim of this retrospective study was to identify risk factors for hospital-acquired Clostridium difficile infection (HA-CDI) in orthopaedic patients. Thirty-two HA-CDI cases were each matched with two controls. Incidence rate was 0.33 cases per 1000 patient-days. Univariate analyses showed that surgery >24 h after admission, antibiotics for treatment, and proton pump inhibitors were associated with HA-CDI. Multivariate analyses revealed that surgery >24h after admissionwas associated with HA-CDI. Patients hospitalized before surgery had a greater risk of HA-CDI, suggesting opportunities to reduce environmental exposure to C. difficile by timelier preoperative medical optimization in the outpatient setting. (C) 2012 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.