Challenges in replicating interventions

Challenges in replicating interventions
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DOI:
10.1016/j.jadohealth.2006.09.005
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发表时间:
2007-06-01
影响因子:
7.6
通讯作者:
Zimmerman, Richard
Zimmerman, Richard
中科院分区:
医学2区
文献类型:
--
作者:
Bell, Stephanie G.;Newcomer, Susan F.;Zimmerman, Richard

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目的:描述和反思一项努力,通过一套6项干预措施,记录有效的青少年风险行为干预措施适应新环境的过程,并提供如何最好地完成这一工作的见解。方法:从1999年开始,美国国立卫生研究院资助了6项研究。这些研究是响应申请请求(RFA)资助的,该请求旨在为青少年复制艾滋病毒预防干预措施。研究人员将选择一项在一个青少年群体中显示有效的降低艾滋病毒风险干预计划,并将其复制到一个新的社区或不同的青少年群体中。这项工作是在系统地记录干预的过程和方面的同时进行的,这些过程和方面被假设为对以社区为基础的文化敏感项目的发展至关重要。复制是为了评估获得合作所需的变化,实施当地可行且有意义的干预措施,并评估新环境下的结果。描述了这一倡议的基本原理以及资助研究人员的目标和适应方法的描述。结果:除了与复制相关的问题外,还讨论了与所有干预措施相关的问题。然后讨论适应的过程和后果。将成功的干预措施“规模化”的进一步挑战没有被讨论。结论:有效干预措施的复制面临实施设计的所有挑战,以及平衡原始干预措施的保真度和对新人群需求的敏感性的额外挑战。(c) 2007年青少年医学学会。版权所有。
Purpose: To describe and reflect on an effort to document, through a set of 6 interventions, the process of adapting effective youth risk behavior interventions for new settings, and to provide insights into how this might best be accomplished.Methods: Six studies were funded by the NIH, starting in 1999. The studies were funded in response to a Request for Applications (RFA) to replicate HIV prevention interventions for youth. Researchers were to select an HIV risk reduction intervention program shown to be effective in one adolescent population and to replicate it in a new community or different adolescent population. This was to be done while systematically documenting those processes and aspects of the intervention hypothesized to be critical to the development of community-based, culturally sensitive programs. The replication was to assess the variations necessary to gain cooperation, implement a locally feasible and meaningful intervention, and evaluate the outcomes in the new setting. The rationale for this initiative and description of the goals and approaches to adaptation of the funded researchers are described.Results: Issues relevant to all interventions are discussed, in addition to those unique to replication. The processes and the consequences of the adaptations are then discussed. The further challenges in taking a successful intervention "to scale" are not discussed.Conclusions: Replications of effective interventions face all of the challenges of implementation design, plus additional challenges of balancing fidelity to the original intervention and sensitivity to the needs of new populations. (c) 2007 Society for Adolescent Medicine. All rights reserved.