Comparison of risk factors for four sexually transmitted infections: results from a study of attenders at three genitourinary medicine clinics in England
Comparison of risk factors for four sexually transmitted infections: results from a study of attenders at three genitourinary medicine clinics in England
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DOI：
10.1136/sti.76.4.262
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发表时间：
2000-08-01
影响因子：
3.6
通讯作者：
Thin, N
中科院分区：
文献类型：
--
作者：
Hughes, G;Catchpole, M;Thin, N
目的：比较英格兰三个大型城市泌尿生殖医学 (GUM) 诊所就诊者四种常见性传播感染 (STI) 的危险因素。方法：收集伦敦两家诊所和谢菲尔德一家诊所就诊者的临床、人口统计和行为数据。在单独的多重 Logistic 回归分析中，使用每种性传播感染的存在作为结果变量，研究了与首次发作的生殖器疣和生殖器单纯疱疹病毒 (HSV) 以及无并发症的淋病和衣原体相关的危险因素。 结果：使用 1996 年 18 238 名患者首次就诊的数据，淋病或衣原体诊断的风险与青少年与 34 岁以上人群相比，加勒比黑人和非洲黑人与白人相比，并且随着性伴侣数量的增加而增加。与白人相比，加勒比黑人和非洲黑人患尖锐湿疣的风险最高，并且与性伴侣的数量无关。虽然尖锐湿疣与年龄较小有关，但与细菌感染相比，其发生率要低得多。生殖器 HSV 诊断与年龄无关。结论：这项针对 GUM 诊所就诊者的研究表明，通过有针对性的性健康促进（特别是针对黑人少数族裔、青少年和多性伴侣者），可以降低细菌性性传播感染的发病率。病毒性性传播感染与人口亚群的关系不太明显，基于更广泛人口的性健康促进方法可能更有效地控制这些感染。
Objective: To compare the risk factors for four common sexually transmitted infections (STIs) in attenders at three large urban genitourinary medicine (GUM) clinics in England.Methods: Clinical, demographic, and behavioural data on attenders at two clinics in London and one in Sheffield were collected. Risk factors associated with first episodes of genital warts and genital herpes simplex virus (HSV), and uncomplicated gonorrhoea and chlamydia were investigated using the presence of each of these STIs as the outcome variable in separate multiple logistic regression analyses.Results: Using data on the first attendance of the 18 238 patients attending the clinics in 1996, the risk of a gonorrhoea or chlamydia diagnosis was strongly associated with teenagers compared with those aged over 34, with black Caribbeans and black Africans compared with whites, and increased with the number of sexual partners. The risk of genital warts br HSV diagnosis was lon est in black Caribbeans and black Africans compared with whites and was not associated with the number of sexual partners. While genital warts were associated with younger age, odds ratios mere much lower compared with those for the bacterial infections. Genital HSV diagnoses were not associated with age.Conclusions: This study of GUM clinic attenders suggests a reduction in the incidence of bacterial STIs may be achievable through targeted sexual health promotion focusing particularly on black ethnic minorities, teenagers, and those with multiple sexual partnerships. Viral STIs were less clearly associated with population subgroups and a broader population based approach to sexual health promotion may be more effective in controlling these infections.