Studying cellular processes and detecting disease with protein microarrays.
Studying cellular processes and detecting disease with protein microarrays.
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使用蛋白质微阵列研究细胞过程并检测疾病。
DOI:
10.1080/03602530500205309
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发表时间:
2005
期刊:
影响因子:
--
通讯作者:
Bollinger,Nikki
中科院分区:
文献类型:
--
作者:
Zangar,RichardC;Varnum,SusanM;Bollinger,Nikki
Protein microarrays are a rapidly developing analytic tool with diverse applications in biomedical research. These applications include profiling of disease markers or autoimmune responses, understanding molecular pathways, protein modifications, and protein activities. One factor that is driving this expanding usage is the wide variety of experimental formats that protein microarrays can take. In this review, we provide a short, conceptual overview of the different approaches for protein microarray. We then examine some of the most significant applications of these microarrays to date, with an emphasis on how global protein analyses can be used to facilitate biomedical research.