HIV SEROPREVALENCE IN A SAMPLE OF TANZANIAN INTRAVENOUS DRUG USERS
HIV SEROPREVALENCE IN A SAMPLE OF TANZANIAN INTRAVENOUS DRUG USERS
复制标题
DOI：
10.1521/aeap.2009.21.5.474
复制
发表时间：
2009-10-01
影响因子：
1.8
通讯作者：
Leshabari, M. T.
中科院分区：
文献类型：
--
作者：
Williams, Mark L.;McCurdy, Sheryl A.;Leshabari, M. T.
最近在撒哈拉以南非洲出现了注射吸毒现象。本研究的目的是评估与坦桑尼亚达累斯萨拉姆注射吸毒者（IDUs）样本中艾滋病毒检测阳性风险增加相关的因素。参与者由受过训练的推广工作人员招募，或由完成研究的注射吸毒者介绍。从315名男性和219名女性注射吸毒者中收集血液标本和自我报告的社会经济和行为数据。采用单变量优势比和多变量logistic回归模型分析数据。42%的样本检测出艾滋病毒呈阳性。一些社会经济、注射和性因素被发现与艾滋病毒检测呈阳性的几率增加有关。多变量分析显示，在过去30天内发生性行为超过81次，过去一个月收入低于10万先令（76美元），在达累斯萨拉姆居住不到5年，以及注射3年与感染风险最大独立相关。在这一注射吸毒者抽样中发现艾滋病毒感染率非常高，这表明注射吸毒可能是撒哈拉以南非洲继续流行的一个因素。与艾滋病毒感染风险增加有关的因素表明，需要进一步研究注射吸毒者的针头使用和性网络。
Injection drug use has recently emerged in sub-Saharan Africa. The purpose of this study was to assess the factors associated with increased risk of testing HIV-positive in a sample of injection drug users (IDUs) in Dar es Salaam, Tanzania. Participants were recruited by a trained outreach worker or were referred by IDUs who had completed the study. Blood specimens and self-reported socioeconomic and behavioral data were collected from 315 male and 219 female IDUs. Data were analyzed using univariate odds ratios and multivariate logistic regression modeling. Forty-two percent of the sample tested HIV-positive. Several socioeconomic, injection, and sexual factors were found to be associated with increased odds of testing HIV-positive. Multivariate analysis showed that having had sex more than 81 times in past 30 days, earning less than 100,000 shillings (US$76) in the past month, residency in Dar es Salaam for less than 5 years, and injecting for 3 years were independently associated with the greatest risk of infection. The rate of HIV infection in this sample of IDUs was found to be very high, suggesting that injection drug use may be a factor in the continuing epidemic in sub-Saharan Africa. The factors associated with increased risk of HIV infection suggest further research is needed on the needle use and sexual networks of IDUs.