Chemodynamic Therapy Combined with Multifunctional Nanomaterials and Their Applications in Tumor Treatment
Chemodynamic Therapy Combined with Multifunctional Nanomaterials and Their Applications in Tumor Treatment
复制标题
化学动力疗法联合多功能纳米材料及其在肿瘤治疗中的应用
DOI：
10.1002/chem.202101514
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发表时间：
2021
期刊：
影响因子：
--
通讯作者：
Tiedong Sun
中科院分区：
文献类型：
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作者：
Zhenghao Yu;Yue Hu;Yuan Sun;Tiedong Sun
在过去的几十年里，放疗和化疗一直是肿瘤治疗的标准方法。然而，放疗和化疗对人体的潜在毒副作用仍然不容忽视。鉴于此，芬顿反应已成为对抗肿瘤细胞的最有效的治疗策略之一。本文就近年来芬顿反应在化学动力学治疗（CDT）方面的研究进展作一综述。此外，还对芬顿反应中应用的一系列先进的纳米多功能材料和工程菌进行了综述。为今后肿瘤的治疗提供指导和奠定基础。
During the past few decades, radiotherapy and chemotherapy have been the standard approaches for tumor treatments. However, the potential toxic effect and side effects of both radiotherapy and chemotherapy on the human body still cannot be neglected. Given this, the Fenton reaction has become one of the most effective treatment strategies to combat tumor cells. This review aims to summarize the recent advances comprehensively and systematically in chemodynamic therapy (CDT) via the Fenton reaction. In addition, a host of the advanced nano‐multifunctional materials and engineering bacteria used in the Fenton reaction were also summarized. This paper would be helpful to provide guidance and lay firm foundations for future tumor treatment.