ORIGIN AND SPREAD OF SLOW WAVES IN CANINE GASTRIC ANTRAL CIRCULAR MUSCLE
ORIGIN AND SPREAD OF SLOW WAVES IN CANINE GASTRIC ANTRAL CIRCULAR MUSCLE
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DOI：
10.1152/ajpgi.1985.249.6.g800
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发表时间：
1985-12-01
影响因子：
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通讯作者：
SANDERS, KM
中科院分区：
文献类型：
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作者：
BAUER, AJ;PUBLICOVER, NG;SANDERS, KM
肌丛和粘膜下丛附近的环状肌细胞所记录的慢波有显著差异。通过测量诱发事件到达两个记录位点之间的潜伏期，在圆形肌肉的三个维度上确定了慢波传导速度。慢波在与圆纤维平行的轴上比在与圆纤维垂直的轴上传播得更快。慢波传播速率也测定在平行轴和垂直轴的纤维在肌肠和粘膜下环状肌。慢波在粘膜下层附近的圆肌传导比在肌丛附近的圆肌传导慢。从传导速度的测量，发展了一种技术，以确定自发慢波在肌肉条的起搏器位置。这些数据表明：(1)慢波起源于多个离散的焦点；（ii）沿胃长轴切割的肌条中，这些病灶主要位于肌条的前部区域；（iii）慢波起源于肌外肠半部分。
Electrical slow waves recorded from circular muscle cells near the myenteric and submucosal plexuses were found to be significantly different. By measuring the latencies between the arrival of evoked events at two recording sites, slow wave conduction velocities were determined in the three dimensions of circular muscle. Slow waves propagated more rapidly in the axis parallel to the circular fibers than in the axes perpendicular to the circular fibers. The rates of slow wave propagation were also determined in axes parallel and perpendicular to fibers in myenteric and submucosal circular muscles. Slow waves conducted more slowly in the circular muscle near the submucosa than in circular muscle near the myenteric plexus. From conduction velocity measurements, a technique was developed to determine the pacemaker site of spontaneous slow waves in a muscle strip. These data demonstrate that (i) slow waves originate from multiple discrete foci; (ii) in muscle strips cut along the long axis of the stomach, these foci are found predominantly in the orad region of the muscle strip and (iii) slow waves originate in the outer myenteric half of the muscle.