Aerobic exercise in subacute stroke improves cardiovascular health and physical performance.
Aerobic exercise in subacute stroke improves cardiovascular health and physical performance.
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DOI：
10.1097/npt.0b013e318274d082
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发表时间：
2012-12
期刊：
影响因子：
--
通讯作者：
Rippee MA
中科院分区：
文献类型：
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作者：
Billinger SA;Mattlage AE;Ashenden AL;Lentz AA;Harter G;Rippee MA
中风后，心血管健康经常受到损害。运动能力降低(VO2峰值)和中风患肢血管系统的变化可能会影响行走等体能表现。关于处方中高强度运动在亚急性中风中的作用的信息很少。这项研究的目的是检验为期8周的有氧运动干预是否会改善心血管健康和体能表现。有10名受试者参加了研究，其中9人完成了干预。受试者年龄6 1.2±4.7岁，卒中后6 6.7±4 1.5d，有轻度运动功能障碍(Fugl-Meyer评分，100.3±2 9.3)。在基线、干预后和一个月随访时进行结果测量。双臂的肱动脉血管舒缩反应性(血流介导的扩张；FMD)评估血管健康，峰值运动试验评估运动能力。6分钟步行(6-MWT)测试用于评估体能。参与者在规定的心率(HR)强度下，每周在卧式踏步机上锻炼三次，持续八周。在基线时，我们报告了臂动脉FMD和低VO2峰值的肢体间差异。干预后，两臂的FMD、静息收缩压(SBP)和6MWT均有显著改善。虽然我们还观察到静息舒张压、心率和VO2峰值的改善，但运动干预后，这些都没有统计学意义，有氧运动在亚急性卒中有利于改善心血管健康，降低心脏风险和改善体能(6MWT)。
Cardiovascular health is often impaired after stroke. Reduced exercise capacity (VO2 peak) and changes in the vascular system in the stroke-affected limb may impact physical performance such as walking. There is little information regarding the role of prescribed moderate-high intensity exercise in subacute stroke. The purpose of this study was to examine whether an 8-week aerobic exercise intervention would improve cardiovascular health and physical performance. Ten subjects were enrolled in the study and 9 completed the intervention. Participants were 61.2 ± 4.7 years old, 66.7 ± 41.5 days post-stroke and had minor motor performance deficits (Fugl-Meyer score, 100.3 ± 29.3). Outcome measures were taken at baseline, post-intervention and one-month follow-up. Brachial artery vasomotor reactivity (flow mediated dilation; FMD) of both arms assessed vascular health and a peak exercise test assessed exercise capacity. The six-minute walk (6-MWT) test was used to assess physical performance. Participants exercised on a recumbent stepper three times per week for eight weeks in a prescribed heart rate (HR) intensity. At baseline, we report between-limb differences in brachial artery FMD and low VO2 peak values. After the intervention, significant improvements were reported in FMD in both arms, resting systolic blood pressure (SBP) and the 6MWT. Although we also observed improvements in resting diastolic BP, HR and VO2 peak values, after the exercise intervention, these were not statistically significant Aerobic exercise in subacute stroke was beneficial for improving cardiovascular health, reducing cardiac risk and improving physical performance (6MWT).