RESERVOIRS FOR HUMAN CAMPYLOBACTERIOSIS

RESERVOIRS FOR HUMAN CAMPYLOBACTERIOSIS
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DOI:
10.1093/infdis/141.5.665
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发表时间:
1980-01-01
影响因子:
6.4
通讯作者:
WANG, WLL
WANG, WLL
中科院分区:
医学2区
文献类型:
--
作者:
BLASER, MJ;LAFORCE, FM;WANG, WLL

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人类胎儿弯曲杆菌肠道感染的流行病学研究。空肠还没有得到很好的理解。为了确定是否存在内源性人类储库,分离C。胎儿亚种比较了几个群体的空肠炎和无症状的成人和儿童。C.从4.1%的腹泻患者和66.7%的也患有腹泻的指示患者的家庭接触者中回收了胎儿空肠。在大多数未经治疗的患者中,微生物的携带从症状发作开始持续不到3周。C.胎儿亚种在272名妇女的阴道植物群中,从无症状个体的粪便中很少发现空肠。家畜,特别是腹泻的幼犬,经常感染弯曲杆菌,可能是人类感染的重要宿主。
The epidemiology of human enteric infection due to Campylobacter fetus ssp. jejuni is not well understood. To determine whether an endogenous human reservoir is present, the rates of isolation of C. fetus ssp. jejuni from several populations of diarrheal and asymptomatic adults and children were compared. C. fetus jejuni was recovered from 4.1% of patients with diarrhea and 66.7% of household contacts of the index patients who also had diarrhea. Carriage of organisms in most untreated patients lasted less than 3 wk from onset of symptoms. C. fetus ssp. jejuni was rarely recovered from the feces of asymptomatic individuals and not at all from the vaginal flora of 272 women. Domestic animals, especially puppies with diarrhea, were frequently infected with Campylobacter and may represent a significant reservoir for human infection.