SYNTHESIS AND IN-VITRO ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS ACTIVITY OF ARTEMISININ (QINGHAOSU)-RELATED TRIOXANES
SYNTHESIS AND IN-VITRO ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS ACTIVITY OF ARTEMISININ (QINGHAOSU)-RELATED TRIOXANES
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DOI：
10.1016/s0960-894x(01)80266-3
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发表时间：
1994-04-07
影响因子：
2.7
通讯作者：
SCHINAZI, RF
中科院分区：
文献类型：
--
作者：
JUNG, MK;SCHINAZI, RF
制备了一系列青蒿素（青蒿素）相关的三环类化合物，并对其体外抗hiv活性进行了测定。其中一种化合物12-正丁基脱氧青蒿素对HIV-1具有良好的抗病毒活性。
A series of artemisinin (qinghaosu)-related trioxanes has been prepared and assayed in vitro for anti-HIV activity. One of these compounds, 12-n-butyldeoxoartemisinin shows a good antiviral activity against HIV-1.