BACTERIAL-COLONIZATION, TRACHEO-BRONCHITIS, AND PNEUMONIA FOLLOWING TRACHEOSTOMY AND LONG-TERM INTUBATION IN PEDIATRIC-PATIENTS
BACTERIAL-COLONIZATION, TRACHEO-BRONCHITIS, AND PNEUMONIA FOLLOWING TRACHEOSTOMY AND LONG-TERM INTUBATION IN PEDIATRIC-PATIENTS
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DOI：
10.1378/chest.76.4.420
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发表时间：
1979-01-01
期刊：
影响因子：
9.6
通讯作者：
BROOK, I
中科院分区：
文献类型：
--
作者：
BROOK, I
在1年的随访中，从27名儿科患者中获得了需氧菌和厌氧菌的系列气管培养物。患者需要气管切开术和延长插管3-12个月。（平均7个半月）。气管吸出物培养物产生1508株致病性需氧菌（969株）和厌氧菌（539株）。最常见的需氧菌株是肺炎链球菌和金黄色葡萄球菌。优势厌氧菌为厌氧革兰氏阳性球菌、具核梭杆菌和脆弱拟杆菌。一种病原体被另一种病原体取代的情况经常发生。24例患者发生气管支气管炎，均伴有肺炎发作。厌氧菌可能是气管切开和长期插管患者定植、气管支气管炎和肺炎的细菌植物群的一部分。
Serial tracheal cultures for aerobic and anaerobic bacteria were obtained from 27 pediatric patients during 1 yr of follow-up. The patients had required tracheostomy and prolonged intubation for periods ranging from 3-12 mo. (average, 7 1/2 mo.). Cultures of tracheal aspirates yielded 1508 isolates of pathogenic aerobic (969 isolates) and anaerobic (539 isolates) bacteria. The most frequent aerobic isolates were Streptococcus pneumoniae and Staphylococcus aureus. The predominant anaerobes were anaerobic gram-positive cocci, Fusobacterium nucleatum and Bacteroides fragilis. Replacement of 1 pathogen by another occurred frequently. Tracheobronchitis occurred in 24 patients, all of whom had episodes of pneumonia. Anaerobic bacteria may be a part of the bacterial flora in colonization, tracheobronchitis and pneumonia in patients with tracheostomy and prolonged intubation.