Prevalence of Venous Thrombosis Following Venovenous Extracorporeal Membrane Oxygenation in Patients With Severe Respiratory Failure
Prevalence of Venous Thrombosis Following Venovenous Extracorporeal Membrane Oxygenation in Patients With Severe Respiratory Failure
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DOI：
10.1097/ccm.0000000000001277
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发表时间：
2015-12-01
影响因子：
8.8
通讯作者：
Barrett, Nicholas A.
中科院分区：
文献类型：
--
作者：
Cooper, Eve;Burns, Janis;Barrett, Nicholas A.
目的：静脉-静脉体外膜肺氧合治疗重症呼吸衰竭越来越普遍。在过去10年中，用于静脉-静脉体外膜氧合的人群、技术和方法发生了显著变化。本研究的目的是描述接受静脉-静脉体外膜肺氧合治疗严重呼吸衰竭的成人拔管后插管血管内深静脉血栓形成的患病率。设计：一项单中心、回顾性、观察性队列、电子记录回顾性研究。设置：三级转诊大学教学医院。患者：患者开始接受静脉-静脉体外膜氧合治疗严重呼吸衰竭。干预措施：无。测量和主要结果：从2011年12月至2014年2月，我们确定了103例开始接受体外膜肺氧合的患者，其中81例存活。我们对88.9%的体外膜肺氧合存活者进行了拔管后静脉多普勒超声检查。深静脉血栓形成的患病率在体外膜肺氧合后的插管血管是8.1/1000插管days在patients who were screened.Conclusions：深静脉血栓形成的患病率拔管从体外膜肺氧合严重呼吸衰竭后是临床显着的，和常规静脉多普勒超声拔管后是必要的，在这一人群。
Objectives: Venovenous extracorporeal membrane oxygenation for patients with severe respiratory failure is increasingly common. There has been a significant change in the population, technology, and approach used for venovenous extracorporeal membrane oxygenation over the last 10 years. The objective of this study is to describe the prevalence of postdecannulation deep vein thrombosis in the cannulated vessel in adults who have received venovenous extracorporeal membrane oxygenation for severe respiratory failure.Design: A single-center, retrospective, observational cohort, electronic note review study.Setting: Tertiary referral university teaching hospital.Patients: Patients commenced on venovenous extracorporeal membrane oxygenation for severe respiratory failure.Interventions: None.Measurements and Main Results: We identified 103 patients commenced on extracorporeal membrane oxygenation with 81 survivors from December 2011 to February 2014. We performed postdecannulation venous Doppler ultrasound in 88.9% of extracorporeal membrane oxygenation survivors. The prevalence of deep vein thrombosis in the cannulated vessel following extracorporeal membrane oxygenation is 8.1/1,000 cannula days in patients who were screened.Conclusions: The prevalence of deep vein thrombosis following decannulation from extracorporeal membrane oxygenation for severe respiratory failure is clinically significant, and routine venous Doppler ultrasound following decannulation is warranted in this population.