CIGARETTE SMOKING AND LUNG HAEMORRHAGE IN GLOMERULONEPHRITIS CAUSED BY AUTOANTIBODIES TO GLOMERULAR BASEMENT MEMBRANE
CIGARETTE SMOKING AND LUNG HAEMORRHAGE IN GLOMERULONEPHRITIS CAUSED BY AUTOANTIBODIES TO GLOMERULAR BASEMENT MEMBRANE
复制标题
肾小球基底膜自身抗体引起的肾小球肾炎中吸烟与肺出血
DOI：
10.1016/s0140-6736(83)90923-6
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发表时间：
1983
期刊：
影响因子：
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通讯作者：
A. Rees
中科院分区：
文献类型：
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作者：
M. Donaghy;A. Rees
对51例肾小球基底膜自身抗体(GBM)所致肾炎患者的吸烟习惯进行了调查。43例合并肺出血，8例无肺出血。从47名患者中获得了完整的吸烟史。在这些人中，37名吸烟者全部患有肺出血，而10名不吸烟者中只有2人患有肺出血。吸烟者与非吸烟者循环抗GBM抗体滴度无显著差异。在1例患者中，恢复吸烟后密切相关的肺出血复发。这些结果在很大程度上解释了在抗GBM疾病中存在不同程度的肺出血。
The smoking habits of 51 patients with glomerulonephritis caused by autoantibodies to the glomerular basement membrane (GBM) were investigated. 43 patients also had pulmonary haemorrhage; 8 did not. A full smoking history was obtained from 47 patients. Of these, all 37 cigarette smokers suffered lung haemorrhage, compared with only 2 of 10 non-smokers. There was no significant difference between the titres of circulating anti-GBM antibodies in smokers and non-smokers. In 1 patient resumption of smoking was closely followed by recrudescence of lung haemorrhage. These results largely explain the variable presence of pulmonary haemorrhage in anti-GBM disease.
DOI：
--
发表时间：
1981
期刊：
Journal of immunology (Baltimore, Md. : 1950)
影响因子：
--
作者：
Jennings,L;Roholt,OA;Pressman,D;Blau,M;Andres,GA;Brentjens,JR
通讯作者：
Brentjens,JR