STUDIES OF THE RADIATION SYNDROME IN DROSOPHILA MELANOGASTER
STUDIES OF THE RADIATION SYNDROME IN DROSOPHILA MELANOGASTER
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DOI：
10.2307/3570358
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发表时间：
1955-01-01
影响因子：
3.4
通讯作者：
WILSON, LP
中科院分区：
文献类型：
--
作者：
KING, RC;WILSON, LP
约6万r的照射可在1天内杀死禁食的成年黑腹果蝇，并在2周内使60%的非禁食果蝇死亡。男性比女性更早死亡。然而，雄鱼很少或根本没有改变磷的周转率，并将体重维持在控制值。相比之下，受辐射的雌性果蝇的生长速度会减慢，但最终会达到超过对照组的体重。受照雌体的磷周转有快、慢两个阶段，并延长了半倍。快半衰期和慢半衰期的位相系统都受到不同程度的辐射影响。然而，照射不影响果蝇各阶段的磷损失量，也不影响两性果蝇的总磷含量。P的生物半衰期正常雌虫为0.9天，辐照雌虫为2.0天，正常或辐照雄虫为1.8天。辐照对肠道从酵母中提取磷的效率没有立竿见影的影响。它确实会立即抑制摄食量，并在治疗6天后对苍蝇的耗氧量产生抑制作用。
Irradiation with approximately 60,000 r kills fasted adult Drosophila melanogaster within 1 day and is lethal to 60% of the non-fasted flies within 2 weeks. Males die sooner than females. However, males show little or no modification of P turnover and maintain their weights at control values. In contrast, the rate of growth of irradiated females is slowed down, but the flies eventually reach weights in excess of controls. Irradiated females have fast and slow phases of P turnover with lengthened half-times. The phase systems of fast and slow half-time are affected to different degrees by irradiation. However, irradiation does not affect the amount of P lost by each phase or the total P content of either sex of flies. The biological half-time for P is 0.9 day for normal females, 2.0 day for irradiated females, and 1.8 day for normal or irradiated males. Irradiation does not have an immediate effect on the efficiency of P extraction from yeast by the gut. It does have an immediate depressing effect on food intake and a depressing effect 6 days after treatment on the oxygen consumption of the flies.