A randomized trial comparing aerobic exercise and resistance exercise with a health education program in older adults with knee osteoarthritis - The Fitness Arthritis and Seniors Trial (FAST)
A randomized trial comparing aerobic exercise and resistance exercise with a health education program in older adults with knee osteoarthritis - The Fitness Arthritis and Seniors Trial (FAST)
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DOI：
10.1001/jama.277.1.25
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发表时间：
1997-01-01
影响因子：
120.7
通讯作者：
Craven, T
中科院分区：
文献类型：
--
作者：
Ettinger, WH;Burns, R;Craven, T
客观。-确定结构化运动计划对膝关节骨关节炎老年人自我报告残疾的影响。一项随机，单盲临床试验，持续18个月，在2个学术医疗中心进行，参与者。共有439名社区居住的成年人，年龄60岁或订单，与放射学明显的膝关节骨关节炎，疼痛，和自我报告的身体残疾。有氧运动计划、抗阻运动计划和健康教育计划。主要结果测量。主要结局是自我报告的残疾评分（范围，1-5）。次要结果是膝关节疼痛评分（范围，1-6），身体功能，X线评分，有氧能力和膝关节肌肉力量的性能指标。共有365名（83%）参与者完成了试验，有氧训练组和阻力训练组的运动处方总体依从性分别为68%和70%。随机化后，有氧运动组的参与者在身体残疾问卷上的校正平均值（+/-SE）得分低10%（1.71+/-0.03 vs 1.90+/-0.04单位; P
Objective.-To determine the effects of structured exercise programs on self-reported disability in older adults with knee osteoarthritis.Setting and Design.-A randomized, single-blind clinical trial lasting 18 months conducted at 2 academic medical centers,Participants.-A total of 439 community-dwelling adults, aged 60 years or order, with radiographically evident knee osteoarthritis, pain, and self-reported physical disability.Interventions.-An aerobic exercise program, a resistance exercise program, and a health education program.Main Outcome Measures.-The primary outcome was self-reported disability score (range, 1-5). The secondary outcomes were knee pain score (range, 1-6), performance measures of physical function, x-ray score, aerobic capacity, and knee muscle strength.Results.-A total of 365 (83%) participants completed the trial, Overall compliance with the exercise prescription was 68% in the aerobic training group and 70% in the resistance training group. Postrandomization, participants in the aerobic exercise group had a 10% lower adjusted mean (+/-SE) score on the physical disability questionnaire (1.71+/-0.03 vs 1.90+/-0.04 units; P