Blood island formation: longstanding observations and modern interpretations
Blood island formation: longstanding observations and modern interpretations
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DOI：
10.1016/j.exphem.2005.06.006
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发表时间：
2005-09-01
影响因子：
2.6
通讯作者：
Yoder, MC
中科院分区：
文献类型：
--
作者：
Ferkowicz, MJ;Yoder, MC
卵黄囊血岛长期以来被认为是胚胎发育过程中血细胞出现的第一个部位。我们对血岛如何形成的理解大部分来自鸡胚胎的研究。类似的过程被认为是活跃在鼠血岛的发展。但是，鸡的血岛形成过程与小鼠的血岛形成过程一致的证据有多强？本文将讨论一些原则的研究，导致两个广泛接受的定义的血岛，并将检查最近的研究在小鼠胚胎中进行，以确定这些流行的定义是否可以直接应用。(c)2005年国际实验血液学学会。由爱思唯尔公司出版
The yolk sac blood islands have long been recognized as the first site for blood cell emergence during embryonic development. Much of our understanding of how blood islands form is derived from studies conducted in chick embryos. Similar processes are thought to be active during murine blood island development. But, how strong is the evidence that the process of blood island formation in the chick coincides with that documented in the mouse? This review will discuss some of the principle studies that led to two widely accepted definitions of blood islands and will examine more recent studies performed in murine embryos to determine whether either of these popular definitions can be directly applied. (c) 2005 International Society for Experimental Hematology. Published by Elsevier Inc.