Neural correlate of vernier acuity tasks assessed by functional MRI (FMRI).
Neural correlate of vernier acuity tasks assessed by functional MRI (FMRI).
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通过功能性 MRI (FMRI) 评估游标敏锐度任务的神经相关性。
DOI：
10.1080/02713680701477815
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发表时间：
2007
影响因子：
2
通讯作者：
Liu,GrantT
中科院分区：
文献类型：
--
作者：
Sheth,KevinN;Walker,BMichael;Modestino,EdwardJ;Miki,Atsushi;Terhune,KylaP;Francis,EllieL;Haselgrove,JohnC;Liu,GrantT
游标敏锐度指的是辨别一条线内微小偏移量的能力。然而，尽管游标敏锐度已经在心理生理上得到了广泛的研究，但它的神经相关性仍然不确定。基于先前的心理物理和电生理学数据，我们假设大脑的纹状体外区域将参与游标敏锐度任务，因此我们设计了事件相关功能磁共振(FMRI)范式来识别参与这一行为的大脑皮质区域。正常受试者识别阈值上和阈值下游标偏移量。结果表明，包括额叶、顶叶、枕叶和小脑区的皮质网络有助于观察、处理、解释和确认短暂呈现的游标偏移量。
Vernier acuity refers to the ability to discern a small offset within a line. However, while Vernier acuity has been extensively studied psychophysically, its neural correlates are uncertain. Based upon previous psychophysical and electrophysiologic data, we hypothesized that extrastriate areas of the brain would be involved in Vernier acuity tasks, so we designed event-related functional MRI (fMRI) paradigms to identify cortical regions of the brain involved in this behavior. Normal subjects identified suprathreshold and subthreshold Vernier offsets. The results suggest a cortical network including frontal, parietal, occipital, and cerebellar regions subserves the observation, processing, interpretation, and acknowledgment of briefly presented Vernier offsets.