Virus transfer between fingerpads and fomites
Virus transfer between fingerpads and fomites
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DOI：
10.1111/j.1365-2672.2010.04814.x
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发表时间：
2010-12-01
影响因子：
4
通讯作者：
Boehm, A. B.
中科院分区：
文献类型：
--
作者：
Julian, T. R.;Leckie, J. O.;Boehm, A. B.
目的：病毒在个体和病原体之间的传播是胃肠道和呼吸道疾病的重要传播途径。本研究探讨如何转移的方向，病毒种类，时间，因为最后洗手，性别和滴度影响病毒转移之间的fingerpad和glass.Methods和结果：六百五十六总传输事件，由20名志愿者使用MS 2，phi X174，和FR表示0.23 +/- 0.22（平均值和标准差）的病毒很容易转移接触。病毒的传播受病毒种类和自上次洗手以来的时间的显著影响。fr噬菌体的转移显著高于MS 2和phi X174。表面之间的病毒转移减少最近洗hands.Conclusions：病毒很容易在皮肤和表面之间的接触。转移的病毒的分数取决于多种因素，包括病毒种类，最近洗手，和转移的方向可能是因为表面的理化interactions.Significance和影响的研究：该研究是第一个提供了一个大的数据集的病毒转移事件描述的集中趋势和分布的分数病毒之间的手指和玻璃。该研究的数据集，沿着探索因素的量化效应量，为研究污染物在疾病传播中的作用提供了信息。
Aims: Virus transfer between individuals and fomites is an important route of transmission for both gastrointestinal and respiratory illness. The present study examines how direction of transfer, virus species, time since last handwashing, gender, and titre affect viral transfer between fingerpads and glass.Methods and Results: Six hundred fifty-six total transfer events, performed by 20 volunteers using MS2, phi X174, and fr indicated 0.23 +/- 0.22 (mean and standard deviation) of virus is readily transferred on contact. Virus transfer is significantly influenced by virus species and time since last handwashing. Transfer of fr bacteriophage is significantly higher than both MS2 and phi X174. Virus transfer between surfaces is reduced for recently washed hands.Conclusions: Viruses are readily transferred between skin and surfaces on contact. The fraction of virus transferred is dependent on multiple factors including virus species, recently washing hands, and direction of transfer likely because of surface physicochemical interactions.Significance and Impact of the Study: The study is the first to provide a large data set of virus transfer events describing the central tendency and distribution of fraction virus transferred between fingers and glass. The data set from the study, along with the quantified effect sizes of the factors explored, inform studies examining role of fomites in disease transmission.