Optimal timing of post-treatment [18F] fluorodeoxyglucose (18F-FDG)–PET/ computed tomography (CT) to identify tumor recurrence, nodal metastasis, and distant metastasis for surveillance and discuss the optimal timing of 18F-FDG-PET/CT examination after th
Optimal timing of post-treatment [18F] fluorodeoxyglucose (18F-FDG)–PET/ computed tomography (CT) to identify tumor recurrence, nodal metastasis, and distant metastasis for surveillance and discuss the optimal timing of 18F-FDG-PET/CT examination after th
复制标题
治疗后[18F]氟脱氧葡萄糖（18F-FDG）-PET/计算机断层扫描（CT）的最佳时机，以识别肿瘤复发、淋巴结转移和远处转移进行监测，并讨论 18F-FDG-PET/CT 检查的最佳时机之后
DOI：
10.1097/mnm.0b013e32835bdfe3
复制
发表时间：
2013
期刊：
影响因子：
1.5
通讯作者：
Kurabayashi T
中科院分区：
文献类型：
--
作者：
Nakamura S;Toriihara A;Okochi K;Watanabe H;Shibuya H;Kurabayashi T
目的评价[18F]氟代脱氧葡萄糖（[18F] fluorodeoxyglucose，[18F] FDG）（18 F-FDG）-PET/计算机断层扫描（CT）以确定肿瘤复发、淋巴结转移，方法对319例头颈部恶性肿瘤患者进行18F-FDG-PET/CT检查，观察治疗后18F-FDG-PET/CT显像的变化，并对18F-FDG-PET/CT显像的时间进行分析。本文对头颈部恶性肿瘤的FDG-PET/CT检查进行了研究。将18 F-FDG-PET/CT结果与组织病理学检查或至少6个月的临床和放射学随访证实的最终诊断进行比较。根据是否存在复发性疾病的临床怀疑，将患者分为两组。分析各组18F-FDG-PET/CT诊断的准确性。患者还根据治疗完成与治疗后18 F-FDG-PET/CT检查之间的时间间隔进行分类。由于时间间隔的诊断准确性的差异也evaluated.Results18 F-FDG-PET/CT的诊断准确性高，两组。18 F-FDG-PET/CT诊断复发性乳腺癌的准确性在治疗结束后2个月内（69%）明显低于治疗结束后2个月（93%）。在其他情况下，应在治疗完成后2个月后进行。
ObjectivesThe aims of this study were to evaluate the ability of [18 F] fluorodeoxyglucose (18 F-FDG)-PET/computed tomography (CT) to identify tumor recurrence, nodal metastases, and distant metastases for surveillance and discuss the optimal timing of 18 F-FDG-PET/CT examination after the completion of treatment for head and neck malignancy.MethodsA total of 319 patients who underwent a post-treatment 18 F-FDG-PET/CT examination for head and neck malignancy were studied. 18 F-FDG-PET/CT findings were compared with the final diagnosis confirmed by histopathological examinations or clinical and radiological follow-up for at least 6 months. Patients were divided into two groups according to the presence or absence of clinical suspicion of recurrent disease. The diagnostic accuracy of 18 F-FDG-PET/CT was analyzed for each group. Patients were also categorized according to the time interval between the completion of treatment and the post-treatment 18 F-FDG-PET/CT examination. Differences in diagnostic accuracy due to the time interval were also evaluated.ResultsThe diagnostic accuracy of 18 F-FDG-PET/CT was high for both groups. The overall accuracy of 18 F-FDG-PET/CT performed within 2 months (69%) after the completion of treatment was significantly inferior to that performed after 2 months (93%).Conclusion18 F-FDG-PET should be performed immediately for patients with clinically suspected recurrent disease. In others, it should be performed at later than 2 months after the completion of the treatment.