Neuropsychiatric changes during the COVID-19 pandemic in multiple sclerosis patients
Neuropsychiatric changes during the COVID-19 pandemic in multiple sclerosis patients
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DOI：
10.1590/0004-282x20200122
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发表时间：
2020-09-01
影响因子：
1.4
通讯作者：
BALGETIR, Ferhat
中科院分区：
文献类型：
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作者：
DEMIR, Caner Feyzi;BILEK, Furkan;BALGETIR, Ferhat
背景：本研究报告了与 Covid-19 隔离经历相关的多发性硬化症 (MS) 患者与焦虑、睡眠质量、抑郁、疲劳和生活质量相关的各种心理反应。目的：本研究的目的是调查 COVID-19 大流行对 MS 患者的神经精神影响，并分析导致心理压力的危险因素。方法：该研究被设计为一项前瞻性、横断面调查研究。在神经病学实践中使用的多种评估工具，包括贝克抑郁量表 (BDI)、贝克焦虑量表 (BAI)、疲劳影响量表 (FIS)、匹兹堡睡眠质量指数 (PSQI) 和多发性硬化症生活质量 54 (MSQOL-54) 在 COVID-19 爆发的早期和高峰阶段（分别为 ESO 和 PSO）进行了前瞻性评估。调查表格是使用 SurveyMonkey 设计的，参与者通过网络链接和二维码参与调查。结果：本研究纳入了 50 名患者。 PSO 的 BDI 分数、PSQI 和 FSI 测量值、认知和社会子量表分数以及 FIS 总分、MSQOL-54 测量值、身体和心理子量表分数以及 MSQOL-54 总分与 ESO 显着不同。与 ESO 测量的患者体重指数值相比，PSO 测量的患者体重指数值显着增加。结论：研究结果为制定心理干预措施提供了基础，可以最大程度地减少睡眠障碍和抑郁症的患病率，并可以改善疫情期间患者的生活质量。
Background: This study reported on a variety of psychological reactions related to anxiety, sleep quality, depression, fatigue, and quality of life in individuals with multiple sclerosis (MS), related to the Covid-19 quarantine experience. Objective: The aim of this study was to investigate the neuropsychiatric effects of the COVID-19 pandemic in MS patients and to analyze the risk factors contributing to psychological stress. Methods: The study was designed as a prospective, cross-sectional survey study. Multiple assessment tools that are used in neurological practice, including Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Fatigue Impact Scale (FIS), Pittsburgh Sleep Quality Index (PSQI), and Multiple Sclerosis Quality of Life-54 (MSQOL-54) were administered prospectively both during the early and the peak stages of COVID-19 outbreak (ESO and PSO, respectively). The survey forms were designed using SurveyMonkey and the participants were participating in the survey via a web link and QR code. Results: Fifty patients were included in the study. BDI scores, PSQI and FSI measurements, cognitive and social subscale scores and total FIS score, MSQOL-54 measurements, physical and mental subscale scores, and total MSQOL-54 score at PSO were significantly different than those at ESO. The body mass index values of the patients increased significantly at PSO compared to those measured at ESO. Conclusions: The results provide a basis for the development of psychological interventions that could minimize the prevalence of sleep disorders and depression and could improve patients' quality of life during the outbreak.