HUMAN URINARY-EXCRETION OF L-HISTIDINE-RELATED COMPOUNDS AFTER INGESTION OF SEVERAL MEATS AND FISH MUSCLE
HUMAN URINARY-EXCRETION OF L-HISTIDINE-RELATED COMPOUNDS AFTER INGESTION OF SEVERAL MEATS AND FISH MUSCLE
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DOI：
10.1016/0020-711x(93)90074-o
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发表时间：
1993-09-01
期刊：
影响因子：
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通讯作者：
YOSHIUE, S
中科院分区：
文献类型：
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作者：
ABE, H;OKUMA, E;YOSHIUE, S
1.鲣鱼肌肉经口给药后，约90%的鹅肌氨酸（Ans）以Ans（8%）和pi-methylHis（82%）的形式迅速排出到尿液中，表明Ans快速分解为pi-methylHis。这也是鸡肌肉摄入的情况。2.鳗鱼肌肉摄入后，肌肽（汽车）的排泄量只有1%的摄入量，而几乎没有增加，发现在他，汽车的组成部分，表明这种必需氨基酸的再利用。牛肉和猪肉的摄入也得到了类似的结果。在所有情况下，这些化合物的尿排泄在摄入后7小时内达到最大值，并在40小时内恢复到无肉饮食的水平。
1. After oral administration of the muscle of skipjack tuna, about 90% of ingested anserine (Ans) was excreted quickly into urine as Ans (8%) and pi-methylHis (82%), indicating the fast decomposition of Ans into pi-methylHis. This was also the case for chicken muscle ingestion.2. After eel muscle ingestion, carnosine (Car) excretion was only 1% of the ingested whereas almost no increase was found in His, a constituent of Car, indicating the re-utilization of this essential amino acid. Similar results were also obtained from beef and pork ingestion.3. In all cases, the urinary excretion of these compounds reached a maximum within 7 hr after ingestion and returned to the level of meat-free diet within 40 hr.