Investigation of photoplethysmogram morphology for the detection of hypovolemic states
Investigation of photoplethysmogram morphology for the detection of hypovolemic states
复制标题
用于检测低血容量状态的光电体积描记形态学研究
DOI：
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发表时间：
2008
期刊：
影响因子：
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通讯作者：
E. Jovanov
中科院分区：
文献类型：
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作者：
P. Cox;C. Madsen;K. Ryan;V. Convertino;E. Jovanov
医务人员和紧急情况第一反应者往往面临着监测和评估受害者的资源非常有限。因此，存在对便携式和低功率的实时流动监测能力的内在需求。这对于危及生命的状况（例如内部老化）的生理监测尤其重要。我们建议使用光电容积描记图（PPG）形态作为低血容量状态的指标，并研究其与血压的相关性。在本文中，我们比较了PPG形态与脉搏传导时间（PTT），这已被调查的临床和门诊应用。根据从使用下体负压（LBNP）作为模拟人体出血模型的实验中获得的数据对指标进行测试。本研究的结果表明，PPG形态与脉压（收缩压减去舒张压）相关，因此是检测和实时跟踪低血容量状态的一个有前途的功能。
Medics and first responders to emergencies are often faced with monitoring and assessing victims with very limited resources. Therefore, there is an inherent need for a real-time ambulatory monitoring capability that is portable and low power. This is particularly important for physiological monitoring of life-threatening conditions such as internal hemorrhaging. We propose the use of photoplethysmogram (PPG) morphology as an indicator of hypovolemic states and study its correlation with blood pressure. In this paper, we compared the PPG morphology with pulse transit time (PTT), which has been investigated for clinical and ambulatory applications. The indicators were tested on data obtained from experiments using lower body negative pressure (LBNP) as a model to simulate hemorrhage in humans. The results of this study indicate that PPG morphology is associated with pulse pressure (systolic minus diastolic blood pressure) and is therefore a promising feature for detection and real-time tracking of hypovolemic states.