Usefulness of 18F-fluorodeoxyglucose-Positron Emission Tomography in Comparison with Methionine-Positron Emission Tomography in Differentiating Solid Hemangioblastoma from Adult Cerebellar Tumors.
Usefulness of 18F-fluorodeoxyglucose-Positron Emission Tomography in Comparison with Methionine-Positron Emission Tomography in Differentiating Solid Hemangioblastoma from Adult Cerebellar Tumors.
复制标题
18F-氟脱氧葡萄糖-正电子发射断层扫描与蛋氨酸-正电子发射断层扫描在区分实体血管母细胞瘤和成人小脑肿瘤中的作用。
DOI：
10.1016/j.wneu.2017.11.054
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发表时间：
2017
影响因子：
2
通讯作者：
N. Hashimoto
中科院分区：
文献类型：
--
作者：
Y. Takahashi;A. Nishio;D. Yamamoto;H. Kamada;N. Hashimoto
背景和目的在患有后颅窝肿瘤的成年人中，肿瘤位于轴内的情况比位于轴外的要少。此外，通过常规磁共振成像有时很难对成人单个小脑肿瘤进行鉴别诊断。应用18F-脱氧葡萄糖(FDG)和蛋氨酸对12例后颅窝转移瘤患者进行正电子发射断层扫描(PET)，其中实性血管母细胞瘤(HB)4例，原发性中枢神经系统淋巴瘤3例，胶质母细胞瘤1例，单发脑转移瘤4例。除1例MET外，其余9例均行蛋氨酸-PET检查。测量肿瘤的最大标准摄取值(SUVmax)，并与病理结果进行比较。结果肝硬变的SUVmax明显低于其他肿瘤(P=0.001)。而HB患者的甲硫氨酸最大摄入量与其他肿瘤的SUVmax无显著差异(P=0.07)。结论FDG-PET有助于鉴别成人小脑肿瘤。
Background and PurposeAmong adults with posterior fossa tumors, an intraaxial location of the tumor is less common than an extraaxial location. Moreover, the differential diagnosis of a single cerebellar tumor in adults is sometimes difficult by conventional magnetic resonance imaging. We aimed to report the findings of positron emission tomography (PET) using 18F-fluorodeoxyglucose (FDG) and methionine in adult patients with intraaxial and solitary metastatic brain tumors.Materials and MethodsFDG-PET was performed on 12 patients with posterior fossa tumors: 4 had solid hemangioblastoma (HB), 3 had primary central nervous system lymphomas, 1 had a glioblastoma, and 4 had single metastatic brain tumors (METs). Methionine-PET was performed on 9 patients except for 1 patient with a MET. The maximum standardized uptake value (SUVmax) of the tumor was measured and compared with pathologic findings.ResultsThe SUVmax of FDG in HB was lower compared with that of other tumors (P= 0.001). On the other hand, the SUVmax of methionine in the HB cases was almost the same as that in other tumors (P= 0.07).ConclusionFDG-PET was helpful in differentiating HBs from adult cerebellar tumors.
影响因子：
3.1
作者：
Juhász C;Nahleh Z;Zitron I;Chugani DC;Janabi MZ;Bandyopadhyay S;Ali-Fehmi R;Mangner TJ;Chakraborty PK;Mittal S;Muzik O
通讯作者：
Muzik O