HOW MANY CONTROLS
HOW MANY CONTROLS
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DOI：
10.1016/0021-9681(76)90073-4
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发表时间：
1976-01-01
期刊：
影响因子：
--
通讯作者：
BROWN, C
中科院分区：
文献类型：
--
作者：
GAIL, M;WILLIAMS, R;BROWN, C
讨论了临床或流行病学研究所需的对照数量。推导并说明了平方根法则、案例节约法则和功率增益递减法则。建议合理申请分配不均等的外观设计。
The number of controls needed for a clinical or epidemiological study is discussed. The square root rule, the case savings rule and the rule of diminishing power gain are developed and illustrated. Judicious applications for designs with unequal allocation are suggested.