EPIDEMIOLOGY OF IDIOPATHIC DILATED AND HYPERTROPHIC CARDIOMYOPATHY - A POPULATION-BASED STUDY IN OLMSTED COUNTY, MINNESOTA, 1975-1984
EPIDEMIOLOGY OF IDIOPATHIC DILATED AND HYPERTROPHIC CARDIOMYOPATHY - A POPULATION-BASED STUDY IN OLMSTED COUNTY, MINNESOTA, 1975-1984
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DOI：
10.1161/01.cir.80.3.564
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发表时间：
1989-09-01
期刊：
影响因子：
37.8
通讯作者：
MELTON, LJ
中科院分区：
文献类型：
--
作者：
CODD, MB;SUGRUE, DD;MELTON, LJ
利用马约诊所和罗切斯特流行病学项目的记录链接系统，该系统访问了明尼苏达州奥姆斯特德县（美国）全体人口的诊断数据，我们在1975-1984年的县居民中确定了45例特发性扩张型心肌病（DCM）和19例肥厚型心肌病（HCM）的新病例。经年龄和性别校正的总体发病率分别为6.0/100，000和2.5/100，000人-年。DCM的发病率从研究的前5年的3.9/100，000人年增加到最后5年的7.9/100，000人年。HCM的相应变化为1.4/100，000人-年至3.6/100，000人-年。截至1985年1月1日，DCM和HCM的年龄和性别调整患病率分别为36.5/100，000和19.7/100，000人口。DCM在55岁以下人群中的患病率为17.9/100，000，其中超过三分之一的人在诊断时为纽约心脏协会功能III级或IV级。这些估计可能是有价值的，在确定潜在的使用卫生保健资源，特别是心脏移植。
Using the records linkage system of the Mayo Clinic and of the Rochester Epidemiology Project, which accesses diagnostic data on the entire population of Olmsted County, Minnesota (USA), we identified 45 new cases of idiopathic dilated cardiomyopathy (DCM) and 19 new cases of hypertrophic cardiomyopathy (HCM) among county residents for the years 1975-1984. Overall age- and sex-adjusted incidence rates were 6.0/100,000 and 2.5/100,000 person-years, respectively. The incidence of DCM doubled from 3.9/100,000 in the first 5 years to 7.9/100,000 person-years in the last 5 years of study. The corresponding change for HCM was from 1.4 to 3.6/100,000 person-years. Age- and sex-adjusted prevalence rates as of January 1, 1985 for DCM and HCM were 36.5/100,000 and 19.7/100,000 population, respectively. The prevalence of DCM in persons less than 55 years old was 17.9/100,000, over a third of whom were New York Heart Association functional Class III or IV at diagnosis. These estimates may be of value in determining the potential use of health care resources, particularly cardiac transplantation.