Insomnia, Sleep Duration, Depressive Symptoms, and the Onset of Chronic Multisite Musculoskeletal Pain
Insomnia, Sleep Duration, Depressive Symptoms, and the Onset of Chronic Multisite Musculoskeletal Pain
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DOI：
10.1093/sleep/zsw030
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发表时间：
2017-01-01
期刊：
影响因子：
5.6
通讯作者：
Dekker, Joost
中科院分区：
文献类型：
--
作者：
Generaal, Ellen;Vogelzangs, Nicole;Dekker, Joost
研究目的：睡眠、抑郁症状和疼痛之间的时间关系尚不清楚。这项纵向研究考察了失眠和睡眠时间是否可以预测6年以上慢性多部位肌肉骨骼疼痛的发生，以及这种联系是否由抑郁症状介导。方法：1860名荷兰抑郁和焦虑研究受试者，在基线水平没有慢性多部位肌肉骨骼疼痛的情况下，进行了超过6年的慢性多部位肌肉骨骼疼痛的随访(慢性疼痛分级问卷)。我们确定了基线失眠(女性健康倡议失眠评定量表=9)和睡眠持续时间(短：=10小时)。结果：失眠(危险比[HR][95%可信区间，95%可信区间]=1.60[1.30-1.96]，p
Study objective: The temporal relationships among sleep, depressive symptoms, and pain are unclear. This longitudinal study examines whether insomnia and sleep duration predict the onset of chronic multisite musculoskeletal pain over 6 years and whether this association is mediated by depressive symptoms.Methods: 1860 subjects of the Netherlands Study of Depression and Anxiety, free from chronic multisite musculoskeletal pain at baseline, were followed up for the onset of chronic multisite musculoskeletal pain over 6 years (Chronic Pain Grade Questionnaire). We determined baseline insomnia (Women's Health Initiative Insomnia Rating Scale >= 9) and sleep duration (short: = 10 hr). Depressive symptoms were assessed at baseline and as a change score over time (Inventory of Depressive Symptomatology).Results: Insomnia (hazard ratio [HR] [95% confidence interval, 95% CI] = 1.60 [1.30-1.96], p