Medical investigation of children with autistic spectrum disorders
Medical investigation of children with autistic spectrum disorders
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DOI：
10.1111/j.1365-2214.2006.00630.x
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发表时间：
2006-09-01
影响因子：
1.9
通讯作者：
Baird, G.
中科院分区：
文献类型：
--
作者：
Cass, H.;Sekaran, D.;Baird, G.
很少有结构良好的研究系统地评估了自闭症谱系障碍儿童的医疗调查协议。这在很大程度上是由于人口的异质性和不断变化的诊断框架。本文综述了迄今为止指导调查策略的研究，并讨论了这些研究如何应用于临床。如果测试在指导治疗或更广泛的管理方法中是有用的，则强调了根据特定的临床表现列出可能存在的条件并使用全面的病史和检查来生成目标疾病的预测试概率的重要性。
Few well-constructed studies have systematically evaluated medical investigation protocols for children with autistic spectrum disorders. This is in large part due to the heterogeneous nature of the population and changing diagnostic frameworks. This review outlines the studies that have directed investigation strategies to date, and discusses how these might be applied in the clinical situation. The importance of listing the conditions that may be present on the basis of the specific clinical presentation, and using a thorough history and examination to generate a pre-test probability of the target disorders is emphasized if tests are to be useful in directing therapy or broader management approaches.