Stereological study of the effect of altitude on the trophoblast cell populations of human term placental villi
Stereological study of the effect of altitude on the trophoblast cell populations of human term placental villi
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DOI：
10.1016/s0143-4004(97)80046-x
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发表时间：
1997-07-01
期刊：
影响因子：
3.8
通讯作者：
Ali, KZM
中科院分区：
文献类型：
--
作者：
Ali, KZM
石蜡包埋的组织学材料进行了检查，从10个胎盘在高海拔地区（3000米）无并发症的妊娠。这是比较低海拔（500米）提供的材料从10胎盘。样本组在母亲年龄、胎龄和产次方面相匹配。在终末和中间绒毛内，细胞滋养层细胞的体积加权平均体积在高海拔地区没有显著变化（低海拔地区为754.1 μ m（3），高海拔地区为796 μ m（3））。高海拔胎盘细胞滋养层细胞所占的绒毛体积分数和每万μ m3绒毛组织细胞核数分别为3.17%和1.86%，明显高于低海拔胎盘的1.05%和0.79%（P
Paraffin-embedded histological material was examined from 10 placentae from uncomplicated pregnancies at high altitude (3000 m). This was compared with material from 10 placentae delivered at low altitude (500 m). The sample groups were matched for maternal age, gestational age and parity. Within terminal and intermediate villi the volume-weighted mean cytotrophoblast cell volume did not significantly change at high altitude (754.1 mu m(3) at low altitude versus 796 mu m(3) at high altitude). The fractional volume of the villi occupied by cytotrophoblastic cells and their nuclei number per 10000 mu m(3) of villous tissue were significantly greater in placenta from high altitude (3.17 and 1.86 per cent, respectively) than those from low altitude (1.05 and 0.79 per cent, respectively) (P