The importance of rectal cancer MRI protocols on iInterpretation accuracy
The importance of rectal cancer MRI protocols on iInterpretation accuracy
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DOI：
10.1186/1477-7819-6-89
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发表时间：
2008-08-20
影响因子：
3.2
通讯作者：
Blomqvist, Lennart
中科院分区：
文献类型：
--
作者：
Suzuki, Chikako;Torkzad, Michael R.;Blomqvist, Lennart
背景：磁共振成像（MRI）用于直肠癌患者的术前局部分期。我们的目的是回顾性研究的影响成像协议上的分期accuracy.Patients和方法：MR检查的37例局部晚期疾病被分为两组，依从性和非依从性，根据成像协议，没有知识的组织病理学结果。符合要求的直肠癌成像方案定义为包括矢状面和轴向平面的T2加权成像，低位直肠肿瘤补充冠状面，以及原发肿瘤水平垂直于直肠的高分辨率平面。不符合这些标准的方案被定义为不合规。组织病理学结果被用作金标准。结果：符合直肠成像协议显示出显着更好的相关性与组织病理学结果关于评估前器官的参与（敏感性和特异性率在依从组分别为86%和94%，分别为50%和33%，在非依从组）。与不符合标准的方案相比，符合标准的成像方案使用的体素尺寸和MR序列数量在统计学上也显著更小。结论：适当的MR成像方案可以更准确地对局部进展期直肠肿瘤进行局部分期，其序列数量较少，无需静脉注射钆对比剂。
Background: Magnetic resonance imaging (MRI) is used for preoperative local staging in patients with rectal cancer. Our aim was to retrospectively study the effects of the imaging protocol on the staging accuracy.Patients and methods: MR-examinations of 37 patients with locally advanced disease were divided into two groups; compliant and noncompliant, based on the imaging protocol, without knowledge of the histopathological results. A compliant rectal cancer imaging protocol was defined as including T2-weighted imaging in the sagittal and axial planes with supplementary coronal in low rectal tumors, alongside a high-resolution plane perpendicular to the rectum at the level of the primary tumor. Protocols not complying with these criteria were defined as noncompliant. Histopathological results were used as gold standard.Results: Compliant rectal imaging protocols showed significantly better correlation with histopathological results regarding assessment of anterior organ involvement (sensitivity and specificity rates in compliant group were 86% and 94%, respectively vs. 50% and 33% in the noncompliant group). Compliant imaging protocols also used statistically significantly smaller voxel sizes and fewer number of MR sequences than the noncompliant protocolsConclusion: Appropriate MR imaging protocols enable more accurate local staging of locally advanced rectal tumors with less number of sequences and without intravenous gadolinium contrast agents.