Design of new-type F-FLC artificial joint coatings via fluorine incorporation and fullerene-like structure construction
Design of new-type F-FLC artificial joint coatings via fluorine incorporation and fullerene-like structure construction
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DOI：
10.1016/j.surfcoat.2020.125419
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发表时间：
2020-03
影响因子：
5.4
通讯作者：
Jia Wang;Y. Qing;L. Xiao;Y. G. Wang-;X. Bao;Yanguo Qin;Jiangfeng Zhang;Kan Zhang
中科院分区：
文献类型：
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作者：
Jia Wang;Y. Qing;L. Xiao;Y. G. Wang-;X. Bao;Yanguo Qin;Jiangfeng Zhang;Kan Zhang
作为人工关节表面改性的一种有效方法，传统的类金刚石膜（DLC）在体内存在磨屑堆积和润滑失效等问题，难以满足长期使用的极端要求，需要针对DLC的长期稳定性进行不断优化。本文设计并成功制备了一种新型的氟化类富勒烯碳（F-FLC）薄膜，通过同时引入氟和构建类富勒烯结构，实现了力学性能和摩擦学性能的双重优化。F-FLC膜作为传统DLC膜的替代物，在复杂的模拟体液中具有最低的摩擦系数（0.032）和磨损率（1.58 × 10− 16 m3/Nm），这主要是由于F-FLC膜中适量的氟元素的掺入以及其特殊的微观结构演变所带来的力学性能的提高。此外，后续的细胞相容性评价表明，具有自由基的F-FLC膜可以保持蛋白质的稳定性和生物活性，从而促进细胞的铺展和增殖。从更长远的角度来看，结合氟的抗腐蚀和抗骨质疏松作用，F-FLC薄膜在下一代关节植入物中具有很大的应用潜力。
As an efficient method for the surface modification of artificial joints, the traditional diamond-like carbon (DLC) film suffers from wear debris accumulation and lubrication failurein vivoand is difficult to meet the extreme requirement for long-service, which suggests that the continuous optimization aimed at DLC long-term stability is needed. Here, we design and successfully prepare a new-type fluorinated fullerene-like carbon (F-FLC) film by means of simultaneous fluorine incorporation and fullerene-like structure construction, and finally achieve the dual optimization of mechanical and tribological properties. As a substitute for the traditional DLC film, the F-FLC film owns the lowest friction coefficient (0.032) and wear rate (1.58 × 10−16m3/Nm) in the complicated simulated body fluid, due to the suitable fluorine incorporation and the promotion of mechanical properties which derives from the special microstructure evolution. In addition, the subsequent cyto-compatibility evaluation demonstrates that the F-FLC film with free radicals could preserve the stability and bioactivity of proteins, and then enhance the cell spreading and proliferation. In the longer view, combined with the anti-corrosion and anti-osteoporosis effects of fluorine, F-FLC film has a great potential for application in the next generation of joint implants.