Air pollution and respiratory infections: the past, present, and future.
Air pollution and respiratory infections: the past, present, and future.
复制标题
空气污染和呼吸道感染：过去、现在和未来。
DOI：
10.1093/toxsci/kfad003
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发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Gowdy,KymberlyM
中科院分区：
文献类型：
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作者：
Monoson,Alexys;Schott,Evangeline;Ard,Kerry;Kilburg-Basnyat,Brita;Tighe,RobertM;Pannu,Sonal;Gowdy,KymberlyM
尽管政府出台了相关法规，但地球仪的空气污染水平仍在持续上升。全球空气污染水平的上升对人类健康造成了不利影响，包括每年700万人过早死亡。其中许多死亡可归因于呼吸道感染发病率的增加。考虑到COVID-19大流行是一场前所未有的公共卫生危机，已夺去全球超过650万人的生命，呼吸道感染作为人类死亡的驱动因素是一个紧迫的问题。因此，了解空气污染与呼吸道感染之间的关系比以往任何时候都更重要，以便实施公共卫生措施，进一步降低发病率和死亡率。本文就空气污染暴露与呼吸道感染相互作用的流行病学和基础科学研究现状进行综述。第一部分将介绍按病原体组织的流行病学研究，然后回顾调查感染机制的基础科学研究，最后讨论需要进一步调查的领域。
Air pollution levels across the globe continue to rise despite government regulations. The increase in global air pollution levels drives detrimental human health effects, including 7 million premature deaths every year. Many of these deaths are attributable to increased incidence of respiratory infections. Considering the COVID-19 pandemic, an unprecedented public health crisis that has claimed the lives of over 6.5 million people globally, respiratory infections as a driver of human mortality is a pressing concern. Therefore, it is more important than ever to understand the relationship between air pollution and respiratory infections so that public health measures can be implemented to ameliorate further morbidity and mortality. This article aims to review the current epidemiologic and basic science research on interactions between air pollution exposure and respiratory infections. The first section will present epidemiologic studies organized by pathogen, followed by a review of basic science research investigating the mechanisms of infection, and then conclude with a discussion of areas that require future investigation.