Flexible coding of object motion in multiple reference frames by parietal cortex neurons
Flexible coding of object motion in multiple reference frames by parietal cortex neurons
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DOI：
10.1038/s41593-020-0656-0
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发表时间：
2020-05
影响因子：
25
通讯作者：
Ryo Sasaki;A. Anzai;D. Angelaki;G. DeAngelis
中科院分区：
文献类型：
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作者：
Ryo Sasaki;A. Anzai;D. Angelaki;G. DeAngelis
神经元在不同的参照系中代表空间信息，但尚不清楚神经参照系是否会随着任务需求的变化而变化，以及这些变化是否可以解释行为。在这项研究中，我们研究了神经元在自我运动过程中如何代表运动物体的方向，而猴子在不同的试验中，在以头部为中心的参考系和以世界为中心的参考系中报告对象方向之间切换。在世界坐标系中计算物体运动时需要自运动信息，但在判断物体在头部坐标系中的运动时应忽略自运动信息。腹侧顶内区域的神经反应受任务参照系的调制，因此群体活动代表了任一参照系中的对象方向。相反，内侧上颞区外侧部分的反应主要代表物体在头部坐标中的运动。我们的发现表明，物体运动的神经表征会随着任务要求的变化而变化。
Neurons represent spatial information in diverse reference frames, but it remains unclear whether neural reference frames change with task demands and whether these changes can account for behavior. In this study, we examined how neurons represent the direction of a moving object during self-motion, while monkeys switched, from trial to trial, between reporting object direction in head- and world-centered reference frames. Self-motion information is needed to compute object motion in world coordinates but should be ignored when judging object motion in head coordinates. Neural responses in the ventral intraparietal area are modulated by the task reference frame, such that population activity represents object direction in either reference frame. In contrast, responses in the lateral portion of the medial superior temporal area primarily represent object motion in head coordinates. Our findings demonstrate a neural representation of object motion that changes with task requirements.