Natural variation in the promoter of TGW2 determines grain width and weight in rice
Natural variation in the promoter of TGW2 determines grain width and weight in rice
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TGW2启动子的自然变异决定了水稻的粒宽和粒重
DOI：
10.1111/nph.16540
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发表时间：
2020-04-16
期刊：
影响因子：
9.4
通讯作者：
Gao, Zhenyu
中科院分区：
文献类型：
--
作者：
Ruan, Banpu;Shang, Lianguang;Gao, Zhenyu
了解不同水稻品种籽粒大小自然变异的遗传基础有助于育种工作者培育高产水稻品种。本文报道了一个新的控制粒宽和粒重的半显性数量性状座位qTGW2的发现。相应的基因TGW2编码细胞数调节因子1(OsCNR1)，位于TGW2上游1818bp的单核苷酸多态(SNP)变异是其表达差异的原因，通过影响颖片细胞的增殖和扩张而导致粒宽和粒重的变化。TGW2与植物细胞周期调节因子KRP1相互作用，负向调节粒宽和粒重。对141份水稻材料进行的TGW2遗传多样性分析表明，TGW2是选择性扫查区的育种目标。本研究结果为揭示水稻籽粒形态和粒重的遗传机制提供了新的思路，并揭示了水稻产量改良的一个有前途的基因。
Understanding the genetic basis of natural variation in grain size among diverse rice varieties can help breeders develop high-yielding rice cultivars.Here, we report the discovery of qTGW2, a new semidominant quantitative trait locus for grain width and weight. The corresponding gene, TGW2, encodes CELL NUMBER REGULATOR 1 (OsCNR1) localized to the plasma membrane.A single nucleotide polymorphism (SNP) variation 1818 bp upstream of TGW2 is responsible for its different expression, leading to alteration in grain width and weight by influencing cell proliferation and expansion in glumes. TGW2 interacts with KRP1, a regulator of cell cycle in plants, to negatively regulate grain width and weight. Genetic diversity analysis of TGW2 in 141 rice accessions revealed it as a breeding target in a selective sweep region.Our findings provide new insights into the genetic mechanism underlying grain morphology and grain weight, and uncover a promising gene for improving rice yield.