Green tea and bone health: Evidence from laboratory studies.
Green tea and bone health: Evidence from laboratory studies.
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DOI：
10.1016/j.phrs.2011.03.012
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发表时间：
2011-08
影响因子：
9.3
通讯作者：
Wang JS
中科院分区：
文献类型：
--
作者：
Shen CL;Yeh JK;Cao JJ;Chyu MC;Wang JS
骨质疏松症是老年人的主要健康问题。流行病学证据表明，饮茶与预防老年人骨质流失之间存在关联。摄入绿茶和绿茶生物活性化合物可能有助于减轻这一人群的骨质流失，降低骨质疏松性骨折的风险。本文综述了绿茶及其生物活性成分对骨骼健康的影响，重点介绍了以下方面：(i)骨质疏松的病因学，（ii）绿茶对骨质和微结构的保护作用的证据，在各种骨质流失模型中，衰老，性激素缺乏，慢性炎症，（iii）讨论绿茶对两种肥胖模型中骨量的影响，（iv）观察短期补充绿茶对绝经后低骨量妇女的影响，(v)绿茶生物活性化合物对骨骼保护作用的可能机制；（vi）绿茶与骨骼健康的总结和未来的研究方向。
Osteoporosis is a major health problem in the elderly. Epidemiological evidence has shown an association between tea consumption and the prevention of bone loss in the elderly population. Ingestion of green tea and green tea bioactive compounds may be beneficial in mitigating bone loss of this population and decreasing their risk of osteoporotic fractures. This review describes the effect of green tea with its bioactive components on bone health with an emphasis on the following: (i) the etiology of osteoporosis, (ii) evidence of osteo-protective impacts of green tea on bone mass and microarchitecture in various bone loss models in which induced by aging, sex hormone deficiency, and chronic inflammation, (iii) discussion of impacts of green tea on bone mass in two obesity models, (iv) observation of short-term green tea supplementation given to postmenopausal women with low bone mass, (v) possible mechanisms for the osteo-protective effects of green tea bioactive compounds, and (vi) a summary and future research direction of green tea and bone health.