Apatite-Forming Ability of Flowable vs. Putty Formulations of Newly Developed Bioactive Glass-Containing Endodontic Cement
Apatite-Forming Ability of Flowable vs. Putty Formulations of Newly Developed Bioactive Glass-Containing Endodontic Cement
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DOI：
10.3390/app11198969
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发表时间：
2021-10-01
影响因子：
2.7
通讯作者：
Noiri, Yuichiro
中科院分区：
文献类型：
--
作者：
Edanami, Naoki;Ibn Belal, Razi Saifullah;Noiri, Yuichiro
本研究比较了 Nishika Canal Sealer BG Multi（分别为 F-NBG 和 P-NBG）的可流动配方和腻子配方的磷灰石形成能力 (AFA) 水平，并试图阐明 F-NBG 和 P-NBG 的 AFA 水平差异的原因。 NBG 样品在模拟体液 (SBF) 或含 1、5 或 10 g/L 牛血清白蛋白的 SBF (BSA-SBF) 中老化，并分析其超微结构、元素组成和拉曼光谱，以识别磷灰石的形成。将 NBG 样品在培养基中的磷酸盐离子消耗率作为磷灰石生长的指标进行评估。还评估了 F-NBG 和 P-NBG 的原始元素组成、钙离子释放和碱化能力水平。除在 10 g/L BSA-SBF 中老化的 F-NBG 外，所有 NBG 样品均检测到明显的磷灰石形成。 P-NBG 比 F-NBG 更快地消耗磷酸根离子。制备的 P-NBG 表面比制备的 F-NBG 显示出更多的硅元素。 P-NBG 比 F-NBG 释放更多的钙离子，尽管它们的碱化能力水平在统计上没有差异。总之，P-NBG 的 AFA 大于 F-NBG，可能是因为 P-NBG 暴露表面硅烷醇基团并释放钙离子的能力更强。
This study compared the apatite-forming ability (AFA) levels of flowable and putty formulations of Nishika Canal Sealer BG Multi (F-NBG and P-NBG, respectively) and attempted to clarify the cause of differences in the AFA levels of F-NBG and P-NBG. NBG samples were aged in simulated body fluid (SBF) or 1-, 5-, or 10-g/L bovine serum albumin-containing SBF (BSA-SBF) and analyzed in terms of their ultrastructures, elemental compositions, and Raman spectra to identify apatite formation. The phosphate ion consumption rates of NBG samples in the media were evaluated as an indicator of apatite growth. The original elemental composition, calcium ion release, and alkalizing ability levels of F-NBG and P-NBG were also evaluated. Apparent apatite formation was detected on all NBG samples except F-NBG aged in 10-g/L BSA-SBF. P-NBG consumed phosphate ions faster than F-NBG. As-prepared P-NBG showed more silicon elements on its surface than as-prepared F-NBG. P-NBG released more calcium ions than F-NBG, although their alkalizing ability levels did not differ statistically. In conclusion, the AFA of P-NBG was greater than that of F-NBG, probably because of the greater ability of P-NBG to expose silanol groups on the surface and release calcium ions.