CO2-driven ocean acidification weakens mussel shell defense capacity and induces global molecular compensatory responses
CO2-driven ocean acidification weakens mussel shell defense capacity and induces global molecular compensatory responses
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二氧化碳驱动的海洋酸化削弱了贻贝壳的防御能力并诱导全球分子补偿反应
DOI：
10.1016/j.chemosphere.2019.125415
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发表时间：
2020
期刊：
影响因子：
8.8
通讯作者：
Liu Guangxu
中科院分区：
文献类型：
--
作者：
Zhao Xinguo;Han Yu;Chen Bijuan;Xia Bin;Qu Keming;Liu Guangxu
海洋吸收大气中的CO2降低了海水pH值，并改变了其中的碳酸盐化学，这一过程被称为海洋酸化（OA）。海洋贻贝是一个家庭的生态和经济重要的双壳类，广泛分布于沿着地区。研究表明，OA极大地扰乱了贻贝的生理功能。然而，潜在的分子反应（例如，是否存在任何分子补偿机制）以及OA影响贻贝壳防御能力的程度在很大程度上仍然未知。厚壳贻贝（Mytilus coruscus）在环境pH（8.1）或两种低pH（7.8和7.4）条件下暴露40天。结果表明，未来的OA将破坏贝壳结构，削弱贝壳强度和贝壳闭合强度，最终降低贻贝贝壳的防御能力。此外，未来的OA也将破坏血淋巴pH和Ca 2+稳态，导致细胞外酸中毒和Ca 2+缺乏。外套膜转录组分析表明，贻贝将采取一系列的分子补偿反应，以减轻这些不利影响;然而，削弱壳防御能力将增加贻贝的易感性捕食者，寄生虫和病原体，从而降低其健身。总的来说，这项研究的结果具有重要的生态和经济意义，并将提高我们对贻贝养殖业和沿海生态系统的未来的理解。
Oceanic uptake of atmospheric CO2is reducing seawater pH and shifting carbonate chemistry within, a process termed as ocean acidification (OA). Marine mussels are a family of ecologically and economically significant bivalves that are widely distributed along coastal areas worldwide. Studies have demonstrated that OA greatly disrupts mussels’ physiological functions. However, the underlying molecular responses (e.g., whether there were any molecular compensation mechanisms) and the extent to which OA affects mussel shell defense capacity remain largely unknown. In this study, the thick shell musselsMytilus coruscuswere exposed to the ambient pH (8.1) or one of two lowered pH levels (7.8 and 7.4) for 40 days. The results suggest that future OA will damage shell structure and weaken shell strength and shell closure strength, ultimately reducing mussel shell defense capacity. In addition, future OA will also disrupt haemolymph pH and Ca2+homeostasis, leading to extracellular acidosis and Ca2+deficiency. Mantle transcriptome analyses indicate that mussels will adopt a series of molecular compensatory responses to mitigate these adverse effects; nevertheless, weakened shell defense capacity will increase mussels’ susceptibility to predators, parasites and pathogens, and thereby reduce their fitness. Overall, the findings of this study have significant ecological and economic implications, and will enhance our understanding of the future of the mussel aquaculture industry and coastal ecosystems.