REDUCED SURVIVAL OF ADULT CULEX-PIPIENS INFECTED WITH RIFT-VALLEY FEVER VIRUS
REDUCED SURVIVAL OF ADULT CULEX-PIPIENS INFECTED WITH RIFT-VALLEY FEVER VIRUS
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DOI：
10.4269/ajtmh.1987.37.403
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发表时间：
1987-09-01
影响因子：
3.3
通讯作者：
BAILEY, CL
中科院分区：
文献类型：
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作者：
FARAN, ME;TURELL, MJ;BAILEY, CL
研究了裂谷热病毒感染对雌性库蚊存活的影响。在蚊子摄入裂谷热病毒的3个实验中，传播病毒的蚊子比不传播病毒的蚊子在14-16天的存活率降低44%，传播感染的蚊子比非传播感染的蚊子存活率降低48%。这些结果得到了其他实验的证实，在这些实验中，接种裂谷热病毒的蚊子与接种稀释剂的蚊子的存活率进行了比较。在对照试验和接种试验中，未感染蚊子的存活时间明显长于感染蚊子。尽管传播性感染的蚊子存活率低于未感染的蚊子，但在感染性血食后的第7天和14-18天，传播和传播率相似。这表明，在第7天至14-18天期间，非播散性个体发展为播散性感染，并具有传播病毒的能力，而较老的传播者死亡的速度大致相同。在该病的预测模型中应考虑裂谷热病毒感染相关的生存降低。
The effect of Rift Valley fever (RVF) viral infection on the survival of female Culex pipiens was examined. In 3 experiments in which mosquitoes ingested RVF virus, there was a 44% decrease in survival to days 14-16 for transmitting vs. nontransmitting mosquitoes, and a 48% decrease in survival for individuals with disseminated vs. nondisseminated infections. These results were corroborated by other experiments in which survival of mosquitoes inoculated with RVF virus was compared with that of those inoculated with diluent. In both the per os and inoculation tests, uninfected mosquitoes survived significantly longer than infected mosquitoes. Even though mosquitoes with disseminated infections had a lower survival rate than did uninfected mosquitoes, dissemination and transmission rates were similar at days 7 and 14-18 after the infectious bloodmeal. This suggests that nondisseminated individuals were developing disseminated infections and becoming capable of transmitting virus between days 7 and 14-18 at approximately the same rate older transmitters were dying. The decreased survival associated with RVF viral infection should be considered in predictive models of this disease.