Size Exclusion Chromatography of Copolymers
Size Exclusion Chromatography of Copolymers
复制标题
共聚物的尺寸排阻色谱法
DOI：
10.1021/ba-1983-0203.ch017
复制
发表时间：
1983
影响因子：
4.1
通讯作者：
A. Hamielec
中科院分区：
文献类型：
--
作者：
L. H. G. Rubio;J. Macgregor;A. Hamielec
Size exclusion chromatography (SEC) of copolymers has two basic requirements: the capability to detect selectively the concentration of the copolymer components in the eluting solution, and to obtain suitable calibration and interpretation for both size and composition fractionation. To calibrate and interpret copolymer fractionation results by using the existing theory, it is necessary to determine the experimental conditions that guarantee either size or composition fractionation. Sufficient knowledge of the hydrodynamic properties of the copolymer molecules in solution is also required to relate copolymer size to molecular weight. This chapter reviews the SEC fractionation of copolymers and outlines techniques used to ensure size separation for styrene—acrylonitrile copolymers. To test the separation mechanism, a number of solvents and column configurations were investigated. Conditions that give mainly size or mainly composition fractionation are discussed, as well as guidelines for the selection of solvent and column configuration. Extensive characterization of styrene—acrylonitrile copolymers, based on size fractionation and careful selection of the detection system, is reported.
