Preference for higher sucrose concentrations in cocaine abusing-dependent patients
Preference for higher sucrose concentrations in cocaine abusing-dependent patients
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DOI：
10.1016/s0022-3956(02)00063-8
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发表时间：
2003-01-01
影响因子：
4.8
通讯作者：
Buyinza, M
中科院分区：
文献类型：
--
作者：
Janowsky, D;Pucilowski, O;Buyinza, M
背景动物研究表明，对相对高浓度的甜味溶液的偏好和对甜味溶液消耗缺乏控制与对酒精的偏好有关。在人类身上也有证据表明，酗酒者更喜欢高浓度的甜味溶液。这项研究旨在确定可卡因使用障碍患者是否也喜欢高浓度的甜味溶液。研究方法：将16例可卡因滥用/依赖患者与16例情感障碍住院对照患者进行比较，以了解他们对增加蔗糖溶液浓度的偏好。患者服用蔗糖水溶液，浓度范围为0.05 - 0.83 M。然后，他们被要求评价他们对每种溶液的偏好程度和甜度。结果：可卡因滥用/依赖患者更倾向于最高蔗糖浓度（0.83M）。结论：上述信息表明，可卡因滥用/依赖患者与酗酒者一样，与住院对照组相反，对高浓度蔗糖有共同偏好。(C)2002年由Elsevier Science Ltd.出版
Background. Animal studies suggest that preference for relatively high concentrations of sweet solutions and lack of control over sweet solution consumption is related to a preference for alcohol over water. There also is evidence in humans that alcoholics prefer high concentration sweet solutions. This study was designed to determine whether patients with cocaine use disorder also prefer high concentrations of sweet solutions. Methods: Sixteen patients with cocaine abuse/dependency were compared with 16 inpatient controls with an affective disorder as to their preferences for increasing concentrations Of Sucrose solutions. Patients were administered aqueous sucrose solutions ranging from 0.05 to 0.83 M. They were then asked to rate their degree of preference for, and the degree of sweetness of each solution. Results: Cocaine abusing/dependent patients significantly more often preferred the highest sucrose concentration (0.83M). Conclusions: The above information suggests that cocaine abusing/dependent patients, like alcoholics, and in contrast to inpatient controls, share a preference for high concentrations of sucrose. (C) 2002 Published by Elsevier Science Ltd.