Diffuse alveolar hemorrhage

Diffuse alveolar hemorrhage
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DOI:
10.1016/j.ccm.2004.04.007
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发表时间:
2004-09-01
影响因子:
5.7
通讯作者:
Schwarz, MI
Schwarz, MI
中科院分区:
医学3区
文献类型:
--
作者:
Collard, HR;Schwarz, MI

文献摘要

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弥漫性肺泡出血是一种医学急症,临床医生必须有一个合适的方法来识别它。弥漫性肺泡出血的原因有很多,包括血管炎、免疫性疾病如肺出血肾炎综合征、胶原血管病和特发性疾病。仔细关注病史、体格检查和有针对性的实验室评估通常会提示潜在原因。弥漫性肺泡出血的诊断仍不确定的患者应进行诊断性支气管镜检查。在有弥漫性肺泡出血和肾脏受累证据的患者中,应考虑肾活检以确定根本原因并帮助指导治疗。
Diffuse alveolar hemorrhage represents a medical emergency, and clinicians must have an expedient approach to its identification. There are many causes of diffuse alveolar hemorrhage, including vasculitides, immunologic conditions such as Goodpasture's syndrome, collagen vascular disease, and idiopathic conditions. Careful attention to the medical history, physical examination, and targeted laboratory evaluation often suggests the underlying cause. Patients in whom the diagnosis of diffuse alveolar hemorrhage remains uncertain should undergo diagnostic bronchoscopy. In patients with evidence of diffuse alveolar hemorrhage and renal involvement, kidney biopsy should be considered to identify the underlying cause and help direct therapy.