Ultrasound and magnetic resonance imaging of healthy paediatric ankles and knees: a baseline for comparison with haemophilic joints
Ultrasound and magnetic resonance imaging of healthy paediatric ankles and knees: a baseline for comparison with haemophilic joints
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DOI：
10.1111/hae.12614
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发表时间：
2015-05-01
期刊：
影响因子：
3.9
通讯作者：
Doria, A. S.
中科院分区：
文献类型：
--
作者：
Keshava, S. N.;Gibikote, S. V.;Doria, A. S.
本研究旨在记录不同年龄组正常儿童踝关节和膝关节的软骨和软组织变化/发现，以用于血友病儿童评估的比较。对7-9岁、10-14岁和15- 18岁三个年龄组的健康男孩，在超声和MRI上记录踝关节/膝关节预定部位的腕关节厚度和软组织变化。为了评估超声和MRI测量的有效性，使用与体内应用的技术和扫描仪相似的琼脂模型进行了离体研究。对42例男孩的20例（48%）膝关节和22例（52%）踝关节进行了评价。随着年龄的增长，关节软骨的厚度减少。在年龄组之间，US和MRI上的软骨测量值在大多数部位存在差异（P
The study was undertaken to document cartilage and soft tissue changes/findings in ankles and knees of normal children of different age groups to be used for comparison in the assessment of children with haemophilia. Cartilage thickness and soft tissue changes were recorded at predetermined sites of ankles/knees on both US and MRI in healthy boys in three age groups: 7-9; 10-14; and 15-18years. To assess the validity of the ultrasound and MRI measurements, an ex vivo study was done using agar phantoms with techniques and scanners similar to those applied in vivo. Twenty (48%) knees and 22 (52%) ankles of 42 boys, were evaluated. There was a reduction in the thickness of joint cartilage with age. A difference in cartilage measurements was noted in most sites between the age groups on both US and MRI (P