Real-World Eligibility for HIV Pre-exposure Prophylaxis Among People Who Inject Drugs.
Real-World Eligibility for HIV Pre-exposure Prophylaxis Among People Who Inject Drugs.
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DOI：
10.1007/s10461-020-02800-w
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发表时间：
2020-08
影响因子：
4.4
通讯作者：
Bruneau, Julie
中科院分区：
文献类型：
--
作者：
Picard, Jonathan;Jacka, Brendan;Hoj, Stine;Laverdiere, Emelie;Cox, Joseph;Roy, Elise;Bruneau, Julie
关键词：
最近的研究强调了使用暴露前预防（PrEP）预防注射吸毒者（PWID）感染艾滋病毒的有效性和意愿，但对现实世界适用性的了解有限。我们的目的是量化在加拿大蒙特利尔的艾滋病毒阴性PWID（n=718）中的艾滋病毒PrEP的真实世界资格。根据美国疾病控制和预防中心（CDC）指南计算合格性，并根据评估HIV风险（ARCH-PWID）风险筛查工具将其与HIV感染风险进行比较。超过三分之一的参与者（37%）有资格接受艾滋病毒PrEP，其中三分之一的人仅因性风险而合格。根据ARCH-PWID，一半的参与者被认为是艾滋病毒感染的高风险，但这两种方法之间的一致性很差。虽然很大一部分PWID有资格获得HIV-PrEP，但需要更好的工具来识别艾滋病毒感染风险较高的PWID。
Recent studies have highlighted the efficacy of and willingness to use pre-exposure prophylaxis (PrEP) to prevent HIV infection among people who inject drugs (PWID), however knowledge of real-world applicability is limited. We aimed to quantify the real-world eligibility for HIV-PrEP among HIV-negative PWID in Montreal, Canada (n=718). Eligibility was calculated according to US Centers for Disease Control and Prevention (CDC) guidelines and compared to risk of HIV acquisition according to the Assessing Risk for HIV (ARCH-PWID) risk screening tool. Over one-third of participants (37%) were eligible for HIV PrEP, with 1/3 of these eligible due to sexual risk alone. Half of participants were considered high risk of HIV acquisition according to ARCH-PWID, but there was poor agreement between the two measures. Although a large proportion of PWID were eligible for HIV-PrEP, better tools that are context- and location-informed are needed to identify PWID at higher risk of HIV acquisition.
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DOI：
10.1097/qad.0000000000001747
发表时间：
2018-03-13
期刊：
AIDS (London, England)
影响因子：
--
作者：
Fu R;Owens DK;Brandeau ML
通讯作者：
Brandeau ML
影响因子：
4.2
作者：
Shrestha R;Karki P;Altice FL;Huedo-Medina TB;Meyer JP;Madden L;Copenhaver M
通讯作者：
Copenhaver M
影响因子：
4.4
作者：
Koechlin FM;Fonner VA;Dalglish SL;O'Reilly KR;Baggaley R;Grant RM;Rodolph M;Hodges-Mameletzis I;Kennedy CE
通讯作者：
Kennedy CE
影响因子：
4.2
作者：
Kapadia, F.;Latka, M. H.;Garfein, R. S.
通讯作者：
Garfein, R. S.
影响因子：
4.4
作者：
Artenie, Andreea Adelina;Roy, Elise;Bruneau, Julie
通讯作者：
Bruneau, Julie