Association between ambient temperature and hypertensive disorders in pregnancy in China
Association between ambient temperature and hypertensive disorders in pregnancy in China
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中国环境温度与妊娠期高血压疾病的关系
DOI：
10.1038/s41467-020-16775-8
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发表时间：
2020-06-10
影响因子：
16.6
通讯作者：
Mu, Dezhi
中科院分区：
文献类型：
--
作者：
Xiong, Tao;Chen, Peiran;Mu, Dezhi
妊娠期高血压疾病（hdp）是主要的围产期疾病。我们对中国2,043,182名孕妇进行了全国队列研究，评估了环境温度与HDP亚组之间的关系，包括先兆子痫或子痫、妊娠期高血压和叠加先兆子痫。在极端温度下，在怀孕前（12周）暴露在非常冷的环境中会增加子痫前期或子痫和妊娠高血压的几率。与孕前相比，在妊娠前半期，温度对子痫前期或子痫与妊娠高血压的影响是相反的。暴露在寒冷环境中会降低患病几率，而暴露在炎热环境中则会增加患病几率。在平均温度下，孕前温度升高会降低先兆子痫或子痫和妊娠高血压的风险。然而，在怀孕的前半段，温度与更高的风险呈正相关。在温度和叠加子痫前期之间没有观察到显著的关联。在这里，我们报告了环境温度与子痫前期或子痫与妊娠高血压之间的密切关系。
Hypertensive disorders in pregnancy (HDPs) are leading perinatal diseases. Using a national cohort of 2,043,182 pregnant women in China, we evaluated the association between ambient temperatures and HDP subgroups, including preeclampsia or eclampsia, gestational hypertension, and superimposed preeclampsia. Under extreme temperatures, very cold exposure during preconception (12 weeks) increases odds of preeclampsia or eclampsia and gestational hypertension. Compared to preconception, in the first half of pregnancy, the impact of temperature on preeclampsia or eclampsia and gestational hypertension is opposite. Cold exposure decreases the odds, whereas hot exposure increases the odds. Under average temperatures, a temperature increase during preconception decreases the risk of preeclampsia or eclampsia and gestational hypertension. However, in the first half of pregnancy, temperature is positively associated with a higher risk. No significant association is observed between temperature and superimposed preeclampsia. Here we report a close relationship exists between ambient temperature and preeclampsia or eclampsia and gestational hypertension.