Geographical distribution and risk factors associated with enteric diseases in Vietnam
Geographical distribution and risk factors associated with enteric diseases in Vietnam
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DOI：
10.4269/ajtmh.2007.76.706
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发表时间：
2007-04-01
影响因子：
3.3
通讯作者：
Miller, Mark A.
中科院分区：
文献类型：
--
作者：
Kelly-Hope, Louise A.;Alonso, Wladimir J.;Miller, Mark A.
在越南，志贺氏菌病、伤寒和霍乱是重要的肠道疾病。为了确定其规模和地理分布，并探讨相关的风险因素，我们研究了1991年至2001年的国家监测数据和潜在的生态决定因素。对每个省的年平均发病率进行了计算和绘图。采用双变量和多元回归分析探讨与选定的环境和人类风险因素的关联。总体而言，每10万人中志贺氏菌病的发病率（中位数，41;平均值，70）高于伤寒（中位数，7;平均值，23）和霍乱（中位数，0.3;平均值，2.7）。志贺氏菌病在中部高地发病率最高，与降雨量和城市贫困显著相关;伤寒流行于湄公河三角洲，与蒸汽压力和河流/溪流饮用水最相关;霍乱主要发生在中部沿海地区，沿着，与降雨量和公共饮用水呈正相关。每种疾病的独特地理模式似乎是由不同生态因素的组合驱动的。
In Vietnam, shigellosis, typhoid fever, and cholera are important enteric diseases. To determine their magnitude and geographical distribution, and explore associated risk factors, we examined national surveillance data from 1991 to 2001 and potential ecological determinants. Average annual incidence rates were calculated and mapped for each province. Bivariate and multiple regression analyses were used to explore associations with selected environmental and human risk factors. Overall, shigellosis rates per 100,000 population (median, 41; mean, 70) were higher and more widespread than rates for typhoid fever (median, 7; mean, 23) and cholera (median, 0.3; mean, 2.7). Shigellosis was highest in the Central Highlands and was significantly associated with rainfall and urban poverty; typhoid fever prevailed in the Mekong River Delta and was most associated with vapor pressure and river/stream drinking water; and cholera predominated along the Central Coastal regions and correlated positively with rainfall and public well drinking water. The distinct geographical patterns of each disease appear to be driven by a combination of different ecological factors.