TISSUE BIOCOMPATIBILITY OF CELLULOSE AND ITS DERIVATIVES
TISSUE BIOCOMPATIBILITY OF CELLULOSE AND ITS DERIVATIVES
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DOI：
10.1002/jbm.820230110
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发表时间：
1989-01-01
期刊：
影响因子：
--
通讯作者：
NOISHIKI, Y
中科院分区：
文献类型：
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作者：
MIYAMOTO, T;TAKAHASHI, S;NOISHIKI, Y
纤维素及其衍生物的组织生物相容性通过两项体内试验进行了检验，一项是活体组织吸收试验，另一项是异物反应试验。检测的样品是再生纤维素和纤维素衍生物：甲基纤维素、乙基纤维素、氨基乙基纤维素、羟乙基纤维素和纤维素多离子复合物。活体组织的体内吸附作用取决于样品的结晶度和化学结构。对于所有检测的样品，异物反应相对温和，表明纤维素可以通过物理和/或化学转化转化为生物相容性材料。
Tissue biocompatibility of cellulose and its derivatives was examined in two in vivo tests, one for absorbance by living tissue and one for foreign body reaction. The samples examined were regenerated celluloses and cellulose derivatives: methyl cellulose, ethyl cellulose, aminoethyl cellulose, hydroxyethyl cellulose, and cellulosic polyion complexes. The in vivo adsorbance by living tissue was found to depend on the degree of crystallinity and the chemical structure of the sample. The foreign body reaction was relatively mild for all the sample examined, showing that cellulose can be converted to biocompatible materials by physical and/or chemical transformation.