Abnormal behaviour of proline in the isothiocyanate degradation.
Abnormal behaviour of proline in the isothiocyanate degradation.
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脯氨酸在异硫氰酸酯降解中的异常行为。
DOI：
10.1515/bchm2.1976.357.2.1505
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发表时间：
1976
期刊：
影响因子：
--
通讯作者：
C. von Holt
中科院分区：
文献类型：
--
作者：
W. Brandt;P. Edman;A. Henschen;C. von Holt
已经观察到脯氨酸残基在测序器分析中经常引发重叠。原因已被证明是一个异常缓慢的裂解反应。对裂解反应的动力学进行了研究，发现裂解反应服从准一级动力学。鸡H2B组蛋白n端部分的4个脯氨酸表明，脯氨酸在序列中的位置不同，反应速率有相当大的差异。
It has been observed that proline residues often initiate overlaps during sequenator analysis. The cause has been shown to be an abnormally slow cleavage reaction. The kinetics of the cleavage reaction has been studied and found to obey pseudo-first-order kinetics. There are considerable differences in reaction rates depending on the position of proline in the sequence, as demonstrated for the four prolines in the N-terminal section of the H2B histone from chicken.