Bone and joint disease in sickle call disease
Bone and joint disease in sickle call disease
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DOI：
10.1016/j.hoc.2005.07.001
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发表时间：
2005-10-01
影响因子：
2.4
通讯作者：
Neumayr, L
中科院分区：
文献类型：
--
作者：
Aguilar, C;Vichinsky, E;Neumayr, L
在镰状细胞病中，各种干扰通常会影响骨骼和关节。穿过骨骼的血管中的血管闭塞事件会导致急性和慢性发病率。血管损伤可能导致代谢和结构变化。关节活动受限，沿着急性和慢性疼痛可严重致残。骨和关节疾病是镰状细胞病患者慢性疼痛的最常见原因。这篇文章强调了镰状细胞病影响健康骨骼和关节功能的方面。
In sickle cell disease, various disturbances commonly affect the bones and joints. Vaso-occlusive events in blood vessels that traverse the bones cause acute and chronic morbidity. Damage of the vessels may result in metabolic and structural changes. Limited joint mobility, along with acute and chromic pain can be severely disabling. Bone and Joint disorders are the most common cause of chronic pain in people who have sickle cell disease. This article highlights aspects of sickle cell disease that affect healthy bone and joint function.