Multiecho dixon fat and water separation method for detecting fibrofatty infiltration in the myocardium.
Multiecho dixon fat and water separation method for detecting fibrofatty infiltration in the myocardium.
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DOI：
10.1002/mrm.21657
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发表时间：
2009-01
影响因子：
3.3
通讯作者：
Arai, Andrew E.
中科院分区：
文献类型：
--
作者：
Kellman, Peter;Hernando, Diego;Shah, Saurabh;Zuehlsdorff, Sven;Jerecic, Renate;Mancini, Christine;Liang, Zhi-Pei.;Arai, Andrew E.
关键词：
基于化学位移脂肪抑制的脂肪和水辨别的常规方法由于显微脂肪的差对比度而降低了表征脂肪浸润的能力。用于水和脂肪分离的多回波狄克逊方法具有优于化学位移脂肪抑制的优点：（1）在单次屏气中采集的水和脂肪图像，避免了误配准，（2）脂肪具有正对比度，（3）与对比前和后期增强成像兼容，（4）不易受部分体积效应的影响，（5）在存在背景场变化的情况下鲁棒，以及（6）对于所实现的带宽，减少了化学位移伪像。所提出的技术成功应用于所有28例研究患者：10项研究的适应症为CAD，其中4例慢性MI患者表现出脂肪浸润; 13项研究排除了致瘤性右心室心肌病（ARVC），其中3例纤维脂肪浸润，2例证实为ARVC; 5例心脏肿块（2例脂肪瘤）。心肌内脂肪造影前CNR明显改善，相对于常规脂肪抑制提高了240%。对于所实施的参数，SNR相对于常规晚期增强降低了30%。用于脂肪和水分离的多回波狄克逊方法提供了一种灵敏的检测心肌内脂肪的方法，具有正信号对比。
Conventional approaches for fat and water discrimination based on chemical shift fat suppression have reduced ability to characterize fatty infiltration due to poor contrast of microscopic fat. The multi-echo Dixon approach to water and fat separation has advantages over chemical-shift fat suppression: (1) water and fat images acquired in a single breath-hold, avoiding mis-registration, (2) fat has positive contrast, (3) compatible with pre-contrast and late enhancement imaging, (4) less susceptible to partial volume effects, (5) robust in the presence of background field variation, and (6) for the bandwidth implemented, chemical-shift artifact is decreased. The proposed technique was applied successfully in all 28 patients studied: 10 studies with indication of CAD of which 4 cases with chronic MI exhibited fatty infiltration; 13 studies to rule out arrhythmogenic right ventricular cardiomyopathy (ARVC) of which there were 3 cases with fibro-fatty infiltration, 2 confirmed with ARVC; 5 cases of cardiac masses (2 lipomas). Precontrast CNR of intramyocardial fat was greatly improved, 240% relative to conventional fat suppression. For the parameters implemented, the SNR was decreased by 30% relative to conventional late enhancement. The multi-echo Dixon method for fat and water separation provides a sensitive means of detecting intramyocardial fat with positive signal contrast.
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影响因子：
19.7
作者：
SZUMOWSKI, J;COSHOW, WR;QUINN, SF
通讯作者：
QUINN, SF
影响因子：
3.3
作者：
Reeder, SB;Faranesh, AZ;McVeigh, ER
通讯作者：
McVeigh, ER
影响因子：
3.3
作者：
Hernando, D.;Haldar, J. P.;Liang, Z. -P.
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Liang, Z. -P.
影响因子：
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作者：
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通讯作者：
Pelc, NJ
影响因子：
1.9
作者：
Bluemke, DA;Krupinski, EA;Marcus, F
通讯作者：
Marcus, F