DEVELOPMENTAL ASPECTS OF EXPERIMENTAL MYOPIA IN CHICKS - SUSCEPTIBILITY, RECOVERY AND RELATION TO EMMETROPIZATION
DEVELOPMENTAL ASPECTS OF EXPERIMENTAL MYOPIA IN CHICKS - SUSCEPTIBILITY, RECOVERY AND RELATION TO EMMETROPIZATION
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DOI：
10.1016/0042-6989(87)90027-7
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发表时间：
1987-01-01
期刊：
影响因子：
1.8
通讯作者：
ADAMS, JI
中科院分区：
文献类型：
--
作者：
WALLMAN, J;ADAMS, JI
在视野的外侧部分被剥夺了形状视觉的小鸡变得严重近视，主要是因为玻璃体腔的延长。近视主要影响视觉剥夺的鼻侧视网膜，非剥夺的颞侧视网膜不受影响。这些变化在生命早期发生得最快，在视力受限仅3天后就很明显。敏感性随年龄增长而下降，与眼轴长度的增长率成正比。如果在出生后的前6周内，由于玻璃体腔的延长停止，视力限制被消除，则近视会恢复。恢复率与近视度数成正相关，与年龄成负相关。屈光状态和变异性的变化模式表明，可能存在一种以依赖于屈光不正的方式调节眼睛生长的主动机制，从而产生正视化。
Chicks deprived of form-vision in the lateral part of their visual fields become severely myopic largely because of elongation of the vitreous chamber. The myopia mostly affects the visually deprived nasal retina; the nondeprived temporal retina is unaffected. These changes occur most rapidly early in life, being evident then after only 3 days of visual restriction. The susceptibility declines with age, being proportional to the rate of increase of axial length. Recovery from this myopia occurs if the visual restriction is removed during the first 6 weeks of life, as a result of the cessation of elongation of the vitreous chamber. The rate of recovery is directly related to the degree of myopia and inversely related to age. The pattern of changes in refrative status and variability argue for the probable existence of an active mechanism regulating eye growth in manner dependent on refractive error, thereby producing emmetropization.