AN TESTING APPARATUS FOR ENDOTHELIAL CELLS' STRESS

AN TESTING APPARATUS FOR ENDOTHELIAL CELLS' STRESS
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DOI:
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发表时间:
2003
期刊:
Journal of Medical Biomechanics
影响因子:
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通讯作者:
Shen Li
Shen Li
中科院分区:
其他
文献类型:
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作者:
Shen Li

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目的:研制一种内皮细胞剪切应力测试装置,为研究培养的内皮细胞生物学特性对血流动力学环境的响应提供实验平台。 方法:应用流体力学和血流动力学理论,研制一种内皮细胞剪切应力测试装置。 结果:在正常和异常生理条件下,该装置均可准确控制和调节剪切应力、垂直应力以及垂直应力的脉动幅度和脉动频率的值。 结论:该装置能够模拟符合机体生理状况的血流动力学环境。
Objective A testing apparatus for shear stress of endothelial cells was developed ,which provided a experimental platform for studying the response of the biological characteristics of cultured endothelial cells to hemodynamic environment. Methods Applying the theories of the hydrodynamics and hemodynamics, a testing apparatus for shear stress to endothelial cells was developed. Results Under both normal and abnormal physiological conditions, control and adjust this apparatus can accurately the values of the shear stress, vertical stress and pulsatile amplitude ,pulsatile frequency of the vertical stress. Conclusion This apparatus can simulate hemodynamic environment coincided with the physiological condition of the body.